Feng Lin

US Patent:

6418537, Jul 9, 2002

Filed:

Jul 8, 1999

Appl. No.:

09/350414

Inventors:

Kewei Yang - San Jose CA
Feng Cheng Lin - Union City CA

Assignee:

Conexant Systems, Inc. - Newport Beach CA

International Classification:

G06F 104

US Classification:

713400, 713503, 710 60

Abstract:

In a preferred embodiment, the invention uses an 8-to-1 data serialization circuit in the transmitter to convert 80-bit parallel 200 MHz data to 10-bit parallel 1. 6 Mb/s date. On the receiver side, data are captured using a forwarded clock and de-serialized. A single global DLL generates 16 master phases without reference to the word boundaries of data being transmitted. These 16 unreferenced phases are input to a phase rotator that, via a series of calibration steps, maps the unreferenced phases into named phases, and in doing so references the phases to the word boundary of the data being transmitted over the slowest data line of the parallel channel. The named phases are then input to a data interpolator in each receiver, which generates 16 local phases. The 16 local phases correspond to the data-bit centers and data-bit edges for each of the 8 bits transferred per major channel clock period. In a bit-centering calibration step, a training pattern is evaluated by each receiver and each data interpolator dynamically adjusts a delay applied to the 16 local phases to establish the local center-data phases in the center of the bits received by the corresponding receiver.

US Patent:

6469988, Oct 22, 2002

Filed:

Jul 8, 1999

Appl. No.:

09/349832

Inventors:

Kewei Yang - San Jose CA
Feng Cheng Lin - Union City CA
Yang Jing Ke - Union City CA

Assignee:

Conexant Systems, Inc. - Newport Beach CA

International Classification:

H04B 320

US Classification:

370289, 370296, 375220, 375346

Abstract:

Signal processing techniques are applied to data rates at state-of-the-art circuit speeds (presently 1. 6 Gbit/sec) by carrying out the signal flow graph of a cannonical FIR filter algorithm using hybrid analog and digital circuit techniques. A plurality of digital to analog converters (DACs) generate analog currents that are the analogue of the tap coefficients of the FIR filter model. The DACs are used as programmable current sources for the tail current sources of respective differential pair stages. Differential delay signals that are the analogue of the FIR delay-line tap signals are connected to the inputs of respective ones of the differential pair stages. The drains of the input devices of the differential pair stages are connected in parallel to common complementary load circuits. The delay signals act to steer the tap coefficient currents to one or the other of the common load circuits. The parallel connection to common load circuits acts to sum the currents sunk (if any) by each of the commonly connected input devices.

US Patent:

7028134, Apr 11, 2006

Filed:

Dec 28, 2000

Appl. No.:

09/750629

Inventors:

Yuanlong Wang - San Jose CA, US
Kewei Yang - San Jose CA, US
Daniel Fu - Sunnyvale CA, US
Feng Cheng Lin - Union City CA, US

Assignee:

Conexant Systems, Inc. - Newport Beach CA

International Classification:

G06F 13/00

US Classification:

710317, 710316, 370360

Abstract:

Communication circuitry is comprised of processing circuitry, parallel channels, and crossbar integrated circuits. The processing circuitry exchanges the communications between communication links and the parallel channels. The parallel channels transfer the communications in parallel with a clock signal. The crossbar integrated circuits receive the communications and the clock signal over the parallel channels, switch the communications based on the clock signal, and transfer the switched communications to the parallel channels.

US Patent:

20100063146, Mar 11, 2010

Filed:

Nov 7, 2007

Appl. No.:

12/514024

Inventors:

M. Edward Medof - Pepper Pike OH, US
Feng Lin - Willoughby OH, US
Qing Li - Cleveland OH, US

International Classification:

A61K 31/24
A61P 27/02

US Classification:

514535

Abstract:

A method for treating or preventing a complement activated T-cell mediated disorder in a subject includes administering a therapeutically effective amount of a pharmaceutical composition to the subject. The pharmaceutical composition includes at least one amidine compound or pharmaceutically acceptable salt.

US Patent:

20120219566, Aug 30, 2012

Filed:

Nov 4, 2010

Appl. No.:

13/505976

Inventors:

M. Edward Medof - Pepper Pike OH, US
Feng Lin - Willoughby OH, US
Michael G. Strainic - Westlake OH, US

International Classification:

A61K 35/14
A61P 43/00
C12N 5/0783
A61K 39/395

US Classification:

4241581, 424 9371, 4241731, 435377

Abstract:

A method of generating a CD4FoxP3 Treg cell, the method includes administering at least one complement antagonist to a naive CD4 T cell at an amount effective to substantially inhibits C3a receptor (C3aR) and/or C5a receptor (C5aR) signal transduction in the CD4 T cell, induce TGF-β1 expression of the CD4 T cell, and induce differentiation of the of the naive CD4 T cell into a CD4FoxP3 Treg cell.

US Patent:

20130202612, Aug 8, 2013

Filed:

Aug 10, 2012

Appl. No.:

13/572141

Inventors:

Feng Lin - Willoughby OH, US
James E. Dennis - Cleveland Heights OH, US
Zhidan Tu - Jiangsu, CN

Assignee:

Case Western Reserve University - Cleveland OH

International Classification:

A61K 38/17
A61K 39/395
A61K 31/7088

US Classification:

4241581, 514 44 A, 4241721, 435375, 514 167, 514 169

Abstract:

A method of treating a degenerative bone condition of a subject includes administering to hematopoietic progenitor cells or osteoclast progenitor cells of the subject at least one agent that substantially reduces the interaction of at least one of C3a or C5a with the C3a receptor (C3aR) and/or C5a receptor (C5aR), a STAT3/IL-6 signaling pathway antagonist, and a combination thereof, the agent being administered to the hematopoietic progenitor cells or osteoclast progenitor cells at an amount effective to inhibit osteoclast differentiation of hematopoietic progenitor cells or osteoclast progenitor cells.

US Patent:

20210275585, Sep 9, 2021

Filed:

Mar 2, 2021

Appl. No.:

17/190297

Inventors:

- Cleveland OH, US
Feng Lin - Cleveland OH, US
Michael G. Strainic - Cleveland OH, US

International Classification:

A61K 35/17
C12N 5/0783

Abstract:

A method of generating a CD4FoxP3Treg cell, the method includes administering at least one complement antagonist to a naive CD4T cell at an amount effective to substantially inhibits C3a receptor (C3aR) and/or C5a receptor (C5aR) signal transduction in the CD4T cell, induce TGF-β1 expression of the CD4T cell, and induce differentiation of the of the naive CD4T cell into a CD4FoxP3Treg cell.

US Patent:

20200325449, Oct 15, 2020

Filed:

Jun 2, 2017

Appl. No.:

16/305911

Inventors:

- Cleveland OH, US
Feng Lin - Cleveland OH, US

International Classification:

C12N 5/0775
A61K 35/28
A61L 33/00

Abstract:

Methods of increasing immunogenic cell viability by administering an immunogenic animal cell and a complement inhibitor to a subject are described. Immunogenic animal cells such as stem cells protected with a coating of complement inhibitor are also described.