Hui Tsu Lu

US Patent:

7838571, Nov 23, 2010

Filed:

Oct 22, 2004

Appl. No.:

10/576635

Inventors:

Christopher N. Bowman - Boulder CO, US
Hui Lu - Dover DE, US
Jeffrey W. Stansbury - Centennial CO, US

Assignee:

The Regents of the University of Colorado - Denver CO

International Classification:

A61K 6/087
A61K 6/08
C08G 75/00

US Classification:

522 44, 522 48, 522167, 522180, 523115, 523116

Abstract:

Photopolymerizable polymer composites based on dimethacrylate systems have been increasingly utilized as dental restorative materials. One of the biggest drawbacks of current dental resin systems is the volume shrinkage and shrinkage induced stresses that arise during the polymerization. Other major problems include incomplete double bond conversion and insufficient wear resistance. This invention involves the development of an entirely novel approach to the photopolymerization process that utilizes thiol-ene systems as low shrinkage and ultra-low shrinkage stress dental restorative materials. Compared with the traditional dimethacrylate dental resins, these novel photopolymerizations have demonstrated a dramatically decreased volume shrinkage, extremely rapid polymerization, abilities to photopolymerize ultrathick materials and achieve much higher conversion, lack of oxygen inhibition and ultra-low shrinkage stress due to low volume shrinkage and drastically delayed gel point conversion. These polymers have thus shown outstanding suitability as dental restorative materials.

US Patent:

20070185230, Aug 9, 2007

Filed:

Mar 8, 2005

Appl. No.:

10/598641

Inventors:

Christopher Bowman - Boulder CO, US
Carioscia Jacquelyn - Broomfield CO, US
Hui Lu - Boulder CO, US
Jeffrey Stansbury - Aurora CO, US

Assignee:

The Regents of the University of Colorado CU Technology Transfer Office - Boulder CO

International Classification:

A61K 6/083

US Classification:

523115000

Abstract:

The present invention provides a dental composition comprising a curable blend of one or more polythiol compounds and one or more polyvinyl compounds; where one or both compounds are oligomers. In one aspect, the polythiol compounds are polythiol oligomers formed by prepolymerization of polyvinyl monomers in the presence of an excess of polythiol monomers. In another aspect, the polyvinyl compounds are polyvinyl oligomers formed by prepolymerization of polythiol monomers in the presence of an excess of polyvinyl monomers. The dental composition may further comprise one or more fillers or photoinitiators known in the art. The invention also comprises methods of making a dental prosthesis comprising the composition described above. Use of the thiol-ene oligomeric system results in cured (polymerized) dental compositions having improved physical properties, including low-shrinkage properties and reduced shrinkage induced-stress, enhanced double bond conversion percentage, and reduced odor.

US Patent:

20080274335, Nov 6, 2008

Filed:

Dec 16, 2005

Appl. No.:

11/722074

Inventors:

Christopher N. Bowman - Boulder CO, US
Sirish Reddy - Hills Boro OR, US
Neil Cramer - Boulder CO, US
Robert P. Sebra - San Francisco CA, US
Hui Lu - Dover DE, US

Assignee:

REGENTS OF THE UNIVERSITY OF COLORADO - Boulder CO

International Classification:

B32B 3/30
C08J 3/28
C08G 75/04

US Classification:

428167, 528376, 528 32, 528364, 528321, 528 75, 522134

Abstract:

The present invention provides a method for modifying a surface of a polymer derived from a mixture comprising a thiol monomer and an olefinic monomer. The method comprises exposing at least a portion of the polymer surface to electromagnetic radiation of sufficient energy to modify the polymer surface. The present invention also provides a polymer derived from polymerizing a mixture of monomers comprising a thiol monomer, an olefinic monomer, and an iniferter.