Dr. Yu graduated from the Bethune Med Univ, Changchun City, Jilin, China in 1986. She works in Mineola, NY and specializes in Neurology and Neuromuscular Medicine. Dr. Yu is affiliated with Winthrop University Hospital.
Antonio J. M. Barbosa, Jr. - Middlebury CT, US Steven Richard Brunette - New Milford CT, US Eugene Richard Hickey - Danbury CT, US Jin Mi Kim - Sandy Hook CT, US Michael David Lawlor - Seymour CT, US René Marc Lemieux - Plantsville CT, US Bryan McKibben - New Milford CT, US Matt Aaron Tschantz - Newtown CT, US Hui Yu - New Milford CT, US
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT
Antonio J.M. BARBOSA - Middlebury CT, US Steven Richard BRUNETTE - New Milford CT, US Eugene Richard HICKEY - Danbury CT, US Jin Mi KIM - Sandy Hook CT, US Michael David LAWLOR - Seymour CT, US Rene Marc LEMIEUX - Plantsville CT, US Bryan MCKIBBEN - New Milford CT, US Matt Aaron TSCHANTZ - Newton CT, US Hui YU - New Milford CT, US
International Classification:
A61K 31/505 A61K 31/397 A61P 37/00
US Classification:
5142102, 514275
Abstract:
Disclosed are novel compounds of formula (I):wherein X, Y, R, Rand Rare as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and type II diabetes. This invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
- Ingelheim am Rhein, DE Kenneth Michael MEYERS - Seymour CT, US Peter Allen NEMOTO - Southbury CT, US Simon SURPRENANT - New Milford CT, US Hui YU - New Milford CT, US
International Classification:
C07D 405/14 C07D 405/04 C07D 413/14 C07D 417/14
Abstract:
The present invention relates to compounds of formula I:and pharmaceutically acceptable salts thereof, wherein R, Rand R, are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.