St. Vincent DePaul College, B.A., 1968; University of Louvain, Belgium, Ph.B., 1969; University of Louvain, Belgium, Ph.B., 1969; University of Louvain, Belgium, 1970; University of Louvain, Belgium, 1970
UNIVERSITY OF TORONTO Toronto, ON 2013 to 2013 Lecturer, Department of ImmunologyTrinity College, University of Toronto Toronto, ON 2012 to 2013 InstructorUNIVERSITY OF TORONTO Toronto, ON 2003 to 2010 Assistant Professor, Department of ImmunologyHOSPITAL FOR SICK CHILDREN Toronto, ON 1999 to 2002 Postdoctoral Research Fellow, Division of Cell BiologyBRANDEIS UNIVERSITY Waltham, MA 1997 to 1999 Postdoctoral Research Fellow, Department of BiologyHARVARD UNIVERSITY Cambridge, MA 1992 to 1994 Teaching Fellow
Education:
Harvard University Cambridge, MA 1990 to 1997 Ph.D. in BiophysicsUniversity of Toronto Toronto, ON 1990 B.Sc. in Physiology and Physics
Mar 2010 to 2000 Risk Management AgentContemporary Services Corp
Apr 2006 to 2000 SupervisorHarbor Distributing Santa Ana, CA Mar 2006 to Jul 2011 Delivery DriverHorizon Beverage Company Avon, MA Nov 2003 to Jan 2006 Delivery DriverFunway Cafe Foxborough, MA Jun 2003 to Jan 2006 Security / DoormanClub K2U South Side Woonsocket, RI Jun 2001 to Jun 2005 Security / DoormanClub K2U South Side Foxborough, MA Nov 2003 to Dec 2004 Event StaffWhitehall CO Norwood, MA Mar 1998 to Mar 2003 Delivery Driver
Medicine Doctors
James Booth, Wayland MA - LPN (Licensed practical nurse)
University Of Alabama Hospital Emergency Room 1802 6 Ave S, Birmingham, AL 35233 (205)9964480 (phone), (205)9755391 (fax)
Education:
Medical School University of Texas Medical School at Houston Graduated: 2009
Languages:
English Spanish
Description:
Dr. Booth graduated from the University of Texas Medical School at Houston in 2009. He works in Birmingham, AL and specializes in Emergency Medicine. Dr. Booth is affiliated with UAB Highlands Hospital and University Of Alabama Hospital.
Methods for detecting human factor VIII or factor VIII-like polypeptides in and isolating it from solutions such as blood or conditioned media are disclosed, together with reagents suitable for the purpose comprising binding moieties that recognize human factor VIII and/or a factor VIII-like polypeptide and form a binding complex therewith. Preferred polypeptide binding moieties are particularly disclosed.
Binding Molecules For Human Factor Viii And Factor Viii-Like Proteins
Jinan Yu - Acton MA, US M. Daniel Potter - Acton MA, US Brian D. Kelley - Medford MA, US Jeffrey S. Deetz - Melrose MA, US James E. Booth - Andover MA, US
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
Binding Molecules For Human Factor Viii And Factor Viii-Like Proteins
Jinan Yu - Acton MA, US M. Daniel Potter - Acton MA, US Marilous Potter, legal representative - Acton MA, US Brian D. Kelley - Medford MA, US Jeffrey S. Deetz - Melrose MA, US James E. Booth - Andover MA, US
Assignee:
Dyax Corp. - Cambridge MA
International Classification:
C12Q 1/70
US Classification:
435 5, 530327, 530345, 435 72, 435 691, 435 696
Abstract:
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
Methods are provided for purification of Factor VIII polypeptides by affinity chromatography and ion exchange chromatography, in which the eluate from the affinity column is diluted with a solution comprising higher salt concentration, or lower non-polar agent concentration than that of the elution solution, prior to passing the diluted solution through the ion exchange column. The affinity matrix may comprise a monoclonal antibody or a peptide ligand. The methods result in improved purification without significant yield loss.
Methods And Compositions For Purifying Human Factor Viii, Factor Viii-Like Proteins Or Fragments Thereof
Jinan Yu - Acton MA, US M. Daniel Potter - Acton MA, US Marilous Potter, legal representative - Acton MA, US Brian D. Kelley - Medford MA, US Jeffrey S. Deetz - Melrose MA, US James E. Booth - Andover MA, US
Assignee:
Dyax Corp. - Cambridge MA
International Classification:
G01N 33/53
US Classification:
435 71, 514 141, 435 792, 435183, 435327, 530413
Abstract:
Provided herein are methods and compositions for purifying human factor VIII, human factor VIII-like peptide or fragments thereof. The methods comprise immobilizing a binding molecule for human factor VIII, human factor VIII-like protein or fragments thereof to a solid support, contacting the immobilized binding molecule with a solution containing the human factor VIII, human factor VIII-like protein or fragments thereof, and purifying the factor by separating the solution from the solid support.
Brian D. Kelley - Medford MA, US James E. Booth - Andover MA, US Paul Brown - Andover MA, US Jon Coffman - Hampstead NH, US Ranganathan Godavarti - Burlington MA, US Tim Iskra - Derry NH, US Shujun Sun - Brentwood NH, US Mary B. Switzer - North Andover MA, US Suresh Vunnum - Burlington MA, US Tianning Yu - Arlington MA, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
G01N 33/53 C07K 14/00
US Classification:
435 71, 436514, 530412
Abstract:
This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0. 1.
Binding Molecules For Human Factor Viii And Factor Viii-Like Proteins
Jinan Yu - Acton MA, US M. Daniel Potter - Acton MA, US Brian D. Kelley - Medford MA, US Jeffrey S. Deetz - Melrose MA, US James E. Booth - Andover MA, US
Assignee:
Dyax Corp. - Cambridge MA
International Classification:
G01N 33/53
US Classification:
435 71, 514 141, 530344, 530412
Abstract:
It is an object of the present invention to provide novel binding molecules for factor VIII and factor VIII-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor VIII polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides. Especially preferred binding molecules according to the invention are short polypeptide sequences, characterized by a stable loop structure.
Brian Kelley - Medford MA, US James Booth - Andover MA, US Paul Brown - Andover MA, US Jon Coffman - Hampstead NH, US Ranganathan Godavarti - Burlington MA, US Tim Iskra - Waltham MA, US Shujun Sun - Brentwood NH, US Mary Switzer - North Andover MA, US Suresh Vunnum - Burlington MA, US Tianning Yu - Arlington MA, US
This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.
Youtube
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BUY: STALK:
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Googleplus
James Booth
Work:
Pact-One Soultions - Network Technician (2007) U.S. Army (C Co 32nd Sig Bn) - Networking Switching Systems Operator/Maintainer (2002-2007)
Education:
Central Washington University - Business, CompTIA - A+, Network+
Relationship:
Married
James “Stu” Booth
Work:
University of Alabama - MD, Emergency Medicine
Education:
University of Alabama Residency Program, University of Texas Medical School at Houston, Covenant College
Tagline:
Husband, father, emergency physician, and techno-nerd
James Booth
Education:
Utah Valley University, Brigham Young University, University of New Mexico, Las Cruces High School, La Cueva High School
YorkMD at UFHSupply Past: Director at Subheat I find the subject of energy efficiency and optimization for maximum performance quite fascinating. I have always felt I had a strong drive towards performance... I find the subject of energy efficiency and optimization for maximum performance quite fascinating. I have always felt I had a strong drive towards performance perfection and love the feeling of being able to squeezing every last drop of capability out of something.
So when I set up my underfloor...
Indonesia and SingaporeAmerican MBA with extensive experience in Southeast Asia. Rotating equipment repair, overhaul, Thermal Spray Coatings, Welding and Cladding. Oil, Gas, Mining... American MBA with extensive experience in Southeast Asia. Rotating equipment repair, overhaul, Thermal Spray Coatings, Welding and Cladding. Oil, Gas, Mining, Pumps, Gas Turbine and general job shops
Bremerton, WASite Monitor at Catholic Community Services Still too tall, have to sit down with kids, not looking for work but work found me - giving back in return for a blessedly remarkable life
Lambert Junior High School Lambert MS 1962-1969, Lambert High School Lambert MS 1966-1969, Delta Academy Marks MS 1969-1972, Leland Academy Leland MS 1972-1974