Jie H Li

US Patent:

8147825, Apr 3, 2012

Filed:

Jan 21, 2005

Appl. No.:

10/597378

Inventors:

Sung Lan Hsia - Miami FL, US
Niven Rajin Narain - Miami FL, US
Jie Li - Miami FL, US
Kathryn J. Russell - Sarasota FL, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 38/43

US Classification:

424 941

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

8293227, Oct 23, 2012

Filed:

Mar 1, 2012

Appl. No.:

13/410085

Inventors:

Sung Lan Hsia - Miami FL, US
Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - Sarasota FL, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 38/43

US Classification:

424 941

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

8562976, Oct 22, 2013

Filed:

Feb 3, 2012

Appl. No.:

13/366224

Inventors:

Sung Lan Hsia - Miami FL, US
Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - Sarasota FL, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 38/43

US Classification:

424 941

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

8586030, Nov 19, 2013

Filed:

Mar 8, 2013

Appl. No.:

13/791313

Inventors:

Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - New York NY, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 38/43

US Classification:

424 941

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

20090144381, Jun 4, 2009

Filed:

Nov 6, 2008

Appl. No.:

12/289924

Inventors:

Jie Li - Mountainside NJ, US
David Tazartes - New York NY, US
Yukun Gou - Wayne PA, US

Assignee:

Barclays Capital Inc. - New York NY

International Classification:

G06F 15/16

US Classification:

709206

Abstract:

A system includes a data store and a server in communication with the data store. The server includes formatting modules having a plurality of formatters, validation modules having a plurality of validators, and a streaming module. The server is configured to receive messages containing financial transaction data from one or more electronic communication networks or one or more client devices. The formatters are configured for each of the electronic communication networks or client devices and convert the messages into an internal format of the streaming system. The validation modules are configured to perform a validation check on the one or more formatted messages.

US Patent:

20140023627, Jan 23, 2014

Filed:

Sep 19, 2013

Appl. No.:

14/031706

Inventors:

Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - New York NY, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 9/00
A61K 45/06
A61K 31/122

US Classification:

424 941, 514690

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animcal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

20210128453, May 6, 2021

Filed:

Jun 12, 2020

Appl. No.:

16/900162

Inventors:

- Miami FL, US
Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - New York NY, US
Karrune V. Woan - Gainesville FL, US
Indushekhar Persaud - Homestead FL, US

Assignee:

University of Miami - Miami FL

International Classification:

A61K 9/00
A61K 47/24
A61K 9/06
A61K 36/53
A61K 31/351
A61K 31/122
A61K 45/06

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animcal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

US Patent:

20140255372, Sep 11, 2014

Filed:

May 20, 2014

Appl. No.:

14/282336

Inventors:

- Miami FL, US
Niven Rajin Narain - Cambridge MA, US
Jie Li - Miami FL, US
Kathryn J. Russell - New York NY, US
Karrune V. Woan - Gainesville FL, US
Indushekhar Persaud - Homestead FL, US

Assignee:

UNIVERSITY OF MIAMI - Miami FL

International Classification:

A61K 9/00
A61K 45/06
A61K 31/122

US Classification:

424 941, 514690, 435375

Abstract:

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.