An artificial bone marrow construct comprising a substrate having at least one well; a three dimensional biocompatible polymer matrix comprising a transparent polymer network containing microspherical voids, wherein the microspherical voids are each connected to at least one other void through inter-connecting pores; at least one LBL coating on a surface of at least one of the polymer network, voids and pores, a population of bone marrow cells comprising stem cells and stromal cells; and at least one bioactive agent. An artificial immune network comprising a polymer matrix with a population of immune cells comprising B-cells and T-cells is disclosed. Methods for testing the toxicity of drugs and other agents against bone marrow cells and methods for making universal blood using the artificial bone marrow constructs are also disclosed.
Name / Title
Company / Classification
Phones & Addresses
Ms. Joan Nichols Vice President
Florenata Solid Surfaces, Inc. Florentine Marble Co.. Inc. Countertops
2921 NW Commerce Park Dr, Boynton Beach, FL 33426 (561)5404053
Joan Nichols Vice President
Florenata Solid Surfaces Education Management
2921 Commerce Park Dr, Boynton Beach, FL 33426 (561)5404053, (561)5404411, (561)5404466
Joan Leslie Nichols Director
Joan Leslie Nichols Foundation, Inc Civic/Social Association
111 SE 12 St, Fort Lauderdale, FL 33316 2101 NE 57 St, Fort Lauderdale, FL 33308
Joan C. Nichols President, Director
Grooming Dales, Inc
4621 NW 31 Ave, Fort Lauderdale, FL 33309
Joan M. Nichols President, Vice President
Florentine Marble Co., Inc
944 Brookdale Dr, Boynton Beach, FL 33435 449 SW 4 Ave, Boynton Beach, FL 33435
Joan M. Nichols President, Vice President
Florenata Solid Surface, Inc Manufacture R of Solid Surface Products
2575 Front St, Cottondale, FL 32431 449 SW 4 Ave, Boynton Beach, FL 33435 944 Brookdale Dr, Boynton Beach, FL 33435
The tissue has trouble moving through structures designed to help shape it, and stem cells used to produce the tissue are slow to replicate, according to Joan Nichols, professor of internal medicine and infectious diseases and associate director of the Galveston National Laboratory at the Universit
Researcher Dr. Joan Nichols said "It's taken us a year to prove to ourselves that we actually did a good job with it. You don't run out immediately and tell the world you have something wonderful until you've proved it to ourselves that we really did something amazing."
This is a crucial discovery seeing as there are currently more than 1,600 people in need of a lung transplant. Joan Nichols, a researcher at the University of Texas Medical Branch (UTMB), told CNN, It's so darn cool. It's been science fiction and we're moving into science fact."
Date: Feb 17, 2014
Category: Health
Source: Google
Researchers grow human lungs in lab for first time
"It's taken us a year to prove to ourselves that we actually did a good job with it. You don't run out immediately and tell the world you have something wonderful until you've proved it to ourselves that we really did something amazing," researcher Dr. Joan Nichols said.
Date: Feb 17, 2014
Category: Health
Source: Google
Scientists grow human lungs in fish tank in record time
"We removed all the cells, all the material in it, and just left the skeleton of the lung, or the scaffold, behind - the pieces of the lungs that are no cells," said UTMB lead researcher Dr. Joan Nichols. "That's why it's so white and pretty and there's no blood in it, it's very pretty looking. And
Dr. Joan Nichols, who was one of the main authors of the research study, said that they filled the fish tank with a kind of nutritional liquid similar to the amniotic fluid inside a womb. The scientists conducted the experiment on the lungs that had been too damaged to be transplanted. They removed
"Throughout March and April 2009, international air travelers on flights from Mexico were unknowingly transporting a novel influenza A (H1N1) virus to the cities they traveled to around the world," said Joan Nichols, associate professor or internal medicine at the University of Texas Medical Branch
"This is really great since it would mean that when vaccine is in short supply that we can manage to provide vaccine to more people," said Joan Nichols, who studies infectious diseases at the Galveston National Laboratory of the University of Texas Medical Branch.