John A Richards

US Patent:

6955788, Oct 18, 2005

Filed:

Dec 11, 2001

Appl. No.:

09/683298

Inventors:

John A. Richards - Middleton MA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

G01N021/00
C12M001/36

US Classification:

422 56, 422 681, 422100, 422131, 4352831, 4352862, 4352864, 436166, 436180, 436501

Abstract:

An alignment apparatus and method are described for accurately and reliably depositing biological materials on a microscope slide or other substrate. A preferred implementation includes a first mounting assembly that enables rotation of deposit elements around a first axis perpendicular to the substrate surface using one or more bearing surfaces concentric with the first axis. A second mounting assembly enables rotation of the deposit elements around a second axis parallel to the depositing surface, and a third mounting assembly enables rotation of the deposit elements around a third axis that is parallel to the depositing surface and perpendicular to the second axis. Various types of deposit elements may be used, such as pins, quills, or jetting elements.

US Patent:

20060034725, Feb 16, 2006

Filed:

Oct 14, 2005

Appl. No.:

11/250985

Inventors:

John Richards - Middleton MA, US

Assignee:

Affymetrix, INC. - Santa Clara CA

International Classification:

C40B 60/08
C12Q 1/68
G01N 33/53

US Classification:

422056000, 435006000, 435007100

Abstract:

An alignment apparatus and method are described for accurately and reliably depositing biological materials on a microscope slide or other substrate. A preferred implementation includes a first mounting assembly that enables rotation of deposit elements around a first axis perpendicular to the substrate surface using one or more bearing surfaces concentric with the first axis. A second mounting assembly enables rotation of the deposit elements around a second axis parallel to the depositing surface, and a third mounting assembly enables rotation of the deposit elements around a third axis that is parallel to the depositing surface and perpendicular to the second axis. Various types of deposit elements may be used, such as pins, quills, or jetting elements.

US Patent:

20230088175, Mar 23, 2023

Filed:

Sep 23, 2021

Appl. No.:

17/482536

Inventors:

- Armonk NY, US
Stephanie Houde - Belmont MA, US
Fernando Carlos Martinez - La Plata, AR
Justin David Weisz - Scarsdale NY, US
John Thomas Richards - Honeoye Falls NY, US

International Classification:

G06F 8/41
G06F 3/0484
G06F 40/58

Abstract:

Embodiments relate to interactive graphical display. A request is processed by a generative system to generate multiple hypotheses of an output in response to the request, a primary hypothesis of the multiple hypotheses having a highest confidence for the output, multiple secondary hypotheses of the multiple hypotheses having a lower confidence than the highest confidence. At least one region of divergence is determined from the primary hypothesis by the multiple secondary hypotheses, the at least one region of divergence having alternatives in the multiple secondary hypotheses, the alternatives in the multiple secondary hypotheses differing from the primary hypothesis. A graphical user interface displays the at least one region of divergence in the primary hypothesis and alternatives in the multiple secondary hypotheses for the at least one region of divergence, the alternatives and primary hypothesis for the at least one region of divergence being displayed as selectable options for a user.