Jonas C Wang

US Patent:

20020001613, Jan 3, 2002

Filed:

Feb 9, 2001

Appl. No.:

09/779069

Inventors:

Susan Niemiec - Yardley PA, US
Glenn Nystrand - Lebanon NJ, US
Jonas Wang - Robbinsville NJ, US

International Classification:

A61K009/127
B01J013/02

US Classification:

424/450000, 264/004100

Abstract:

The present invention relates to a method of making a liposome, said method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, said lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a cavitational sheer force to said mixture to form said liposome; wherein said cavitational force is created by contacting said mixture with a member that vibrates at an ultrasonic frequency.

US Patent:

20020010414, Jan 24, 2002

Filed:

Feb 28, 2001

Appl. No.:

09/795908

Inventors:

Anthony Coston - Stockton NJ, US
Ying Sun - Belle Mead NJ, US
Ralph Oakeson - Racine WI, US
Stephen Wisniewski - Doylestown PA, US
Jonas Wang - West Windsor NJ, US

International Classification:

A61N001/30

US Classification:

604/020000

Abstract:

The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating said membrane with an electric current from an array of treatment electrodes; and utilizing a driving force to move said molecule through said perforated membrane.

US Patent:

20020048558, Apr 25, 2002

Filed:

Jul 26, 2001

Appl. No.:

09/916019

Inventors:

Susan Niemiec - Yardley PA, US
Jonas Wang - Robbinsville NJ, US
Stephen Wisniewski - Doylestown PA, US
Kurt Stenn - Princeton NJ, US
Gwang Lu - Plainsboro NJ, US

International Classification:

A61K007/075
A61K007/08

US Classification:

424/070220, 424/070310

Abstract:

This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid/surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.

US Patent:

20020119188, Aug 29, 2002

Filed:

Aug 27, 2001

Appl. No.:

09/939878

Inventors:

Susan Niemiec - Yardley PA, US
Glenn Nystrand - Lebanon NJ, US
Jonas Wang - West Windsor NJ, US

International Classification:

A61K009/127
B01J013/02

US Classification:

424/450000, 264/004100

Abstract:

The present invention relates to a method of making a liposome, the method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, the lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a shear force to the mixture to form the liposome; wherein the shear force is created by passing the mixture by a member at a velocity sufficient to create turbulence in the mixture.

US Patent:

20030206932, Nov 6, 2003

Filed:

Aug 7, 2002

Appl. No.:

10/213714

Inventors:

Jonas Wang - Robbinsville NJ, US
Mohammed Yusuf - Edison NJ, US
Norihiro Yamamoto - Koriyama-shi, JP
Satoshi Kazama - Sukagawa-shi, JP
Christopher Stahl - Hawthorne CA, US
Jean Holland - Doylestown PA, US
Kamran Mather - Agoura Hills CA, US
Margaret Aleles - Gladstone NJ, US
Sachio Hamada - St. Germain, FR
Curtis Cole - Langhorne PA, US
Stephen Wisniewski - Doylestown PA, US

International Classification:

A61K007/00
A61K031/23
A61K031/07

US Classification:

424/401000, 514/725000, 514/552000

Abstract:

Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability

US Patent:

51108097, May 5, 1992

Filed:

Oct 23, 1990

Appl. No.:

7/601958

Inventors:

Jonas Wang - Robbinsville NJ
Bhiku Patel - Amherst NY
Stacley Au - Tonawanda NY
Hemanshu Shah - Williamsville NY

Assignee:

Bristol-Myers Squibb Company - New York NY

International Classification:

A61K 906
A61K 31415
A61K 3157

US Classification:

514171

Abstract:

Stable anhydrous gel formulations for topical antifungal use contain an imidazole, a steroid, a co-solvent system comprising monohydric and dihydric alcohols, and a hydroxyalkylcellulose gellant.

US Patent:

50029380, Mar 26, 1991

Filed:

Mar 15, 1989

Appl. No.:

7/323727

Inventors:

Jonas Wang - Robbinsville NJ
Bhiku Patel - Amherst NY
Stacley Au - Tonawanda NY
Hemanshu Shah - Williamsville NY

Assignee:

Bristol-Myers Squibb Company - New York NY

International Classification:

A61K 910
A61K 3156
A61K 31415

US Classification:

514171

Abstract:

An antifungal gel composition, effective at 0. 2-2. 0% by weight of an imidazole antifungal agent and 0. 01-2. 5% by weight of a 17-ester corticosteroid antiinflammatory agent, is provided for topical administration. This composition is highly effective in treating fungal infections and is capable of being stored without refrigeration for long periods of time without losing therapeutic effectiveness and while maintaining the uniformity and stability of the gel.

US Patent:

55122892, Apr 30, 1996

Filed:

Jun 8, 1995

Appl. No.:

8/495737

Inventors:

Chung-Ye Tseng - Middletown NJ
Jonas Wang - Robbinsville NJ
Marilyn Hudson - Randolph NJ

Assignee:

Johnson & Johnson Consumer Products, Inc. - Skillman NJ

International Classification:

A61F 200
A61F 606

US Classification:

424426

Abstract:

A personal lubricant composition containing an antiviral, alkylphenoxypolyethoxyethanol spermicide, a water soluble polymer gel matrix and a solubilizer which permits the spermicide to be compatible with the gel matrix. Preferably, a polyethoxylated compound such as polyethoxylated castor oil may be used.