Katherine E Stuart

US Patent:

20180043057, Feb 15, 2018

Filed:

Oct 2, 2017

Appl. No.:

15/722312

Inventors:

- Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61L 27/36
A61K 35/12
A61K 35/22
A61L 27/54
A61L 27/22
A61L 27/50
A61L 27/52
A61K 9/00
A61K 38/18

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction The manufacturing methods take advantage of a new recognition that bioactive gels from. ECM material can he created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels

US Patent:

20170043056, Feb 16, 2017

Filed:

Oct 11, 2016

Appl. No.:

15/290445

Inventors:

- Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61L 27/36
A61L 27/54

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction, The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

US Patent:

20160129153, May 12, 2016

Filed:

Dec 15, 2015

Appl. No.:

14/969800

Inventors:

- Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61L 27/36
A61L 27/52
A61L 27/22
A61L 27/54

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

US Patent:

20150335786, Nov 26, 2015

Filed:

Jul 29, 2015

Appl. No.:

14/811993

Inventors:

- Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61L 27/36
A61L 27/54
A61L 27/52
A61L 27/50

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

US Patent:

20140342007, Nov 20, 2014

Filed:

Jul 16, 2014

Appl. No.:

14/332465

Inventors:

- Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61K 35/22
A61K 35/12
A61K 38/18

US Classification:

424499, 424520, 424558

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

US Patent:

20140227362, Aug 14, 2014

Filed:

Feb 7, 2014

Appl. No.:

14/174980

Inventors:

Kimberly A. Kentner - Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61K 35/12
A61K 38/18

US Classification:

424520, 514 91, 514 76, 514 81

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.

US Patent:

20140227364, Aug 14, 2014

Filed:

Feb 7, 2014

Appl. No.:

14/174996

Inventors:

Kimberly A. Kentner - Columbia MD, US
Katherine A. Stuart - Columbia MD, US
Abram D. Janis - Columbia MD, US

International Classification:

A61K 35/22
A61K 9/00

US Classification:

424551, 424553, 424558

Abstract:

The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.