The present invention provides compounds and methods for attaching fluorescent labels to biological molecules such as nucleotides. The compounds and methods are useful for biological assays including DNA modification reactions.
Daniel R. Draney - Lincoln NE, US Lael Cheung - Lincoln NE, US
International Classification:
C07D 471/04
US Classification:
5303913, 546113, 530408
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented:wherein Q is a portion of a polymethine bridge selected from the group consisting of:Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Daniel R. Draney - Lincoln NE, US Mark Cradduck - Lincoln NE, US Lael Cheung - Lincoln NE, US Kousik Kundu - Lincoln NE, US William M. Volcheck - Lincoln NE, US
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented:Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented:Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Compounds are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. Bioconjugate cyanine compounds of Formula II are presented:wherein Q is a portion of a polymethine bridge selected from the group consisting of:
Bachem
Business Development Manager
Li-Cor Biosciences Sep 2013 - Jul 2014
Market Innovation Scientist, Biotechnology
Li-Cor Biosciences Sep 2013 - Jul 2014
Market Innovation Senior Scientist, Biotechnology
Li-Cor Biosciences Sep 2012 - Aug 2013
Scientist, Chemistry R and D
Li-Cor Biosciences May 2010 - Aug 2012
Chemist, Translational Research
Education:
Uc Irvine 2003 - 2008
University of Pennsylvania 1998 - 2002
Marjory Stoneman Douglas High School 1995 - 1998
Highland Oaks Middle School 1992 - 1995
Cooper City High School
Skills:
Chemistry Biotechnology Molecular Biology R&D Biochemistry Drug Discovery Life Sciences Fluorescence Lifesciences Research Hplc Protein Chemistry Nmr Chromatography Research and Development Mass Spectrometry Organic Chemistry Cell Culture Bioconjugate Chemistry High Performance Liquid Chromatography Market Research Organic Synthesis Nuclear Magnetic Resonance Peptide Synthesis Market Analysis