Li Chen

US Patent:

6379381, Apr 30, 2002

Filed:

Sep 3, 1999

Appl. No.:

09/390069

Inventors:

Syed F. A. Hossainy - Fremont CA
Li Chen - San Jose CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61F 206

US Classification:

623 142, 623 143, 623 115, 623 237

Abstract:

An implantable prosthesis, for example a stent, is provided that is capable of being loaded with substances. In one example, the prosthesis is a cylindrical-shaped body having depots or pores formed thereon. The depots can be formed at preselected locations on the body of the prosthesis and can have a preselected depth, size, and shape. The depots can have various shapes including a cylindrical or a conical shape. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots.

US Patent:

6395326, May 28, 2002

Filed:

May 31, 2000

Appl. No.:

09/583371

Inventors:

Daniel Castro - Santa Clara CA
Steven Wu - Santa Clara CA
Kevin L. Woolbright - Sunnyvale CA
Kurt W. Scheinpflug - Sunnyvale CA
Syed F. A. Hossainy - Fremont CA
Li Chen - San Jose CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61L 2700

US Classification:

427 224, 427 225, 427 228, 427 23, 427261, 427286, 427287

Abstract:

A patterned coating on a prosthesis, for example a stent, and a method for forming the coating are disclosed. Additionally, an apparatus for forming the patterned coating is disclosed.

US Patent:

6452685, Sep 17, 2002

Filed:

Sep 20, 2001

Appl. No.:

09/957478

Inventors:

Jon Opsal - Livermore CA
Li Chen - Fremont CA

Assignee:

Therma-Wave, Inc. - Fremont CA

International Classification:

G01B 1124

US Classification:

356601, 356445, 356448

Abstract:

An apparatus for characterizing multilayer samples is disclosed. An intensity modulated pump beam is focused onto the sample surface to periodically excite the sample. A probe beam is focused onto the sample surface within the periodically excited area. The power of the reflected probe beam is measured by a photodetector. The output of the photodetector is filtered and processed to derive the modulated optical reflectivity of the sample. Measurements are taken at a plurality of pump beam modulation frequencies. In addition, measurements are taken as the lateral separation between the pump and probe beam spots on the sample surface is varied. The measurements at multiple modulation frequencies and at different lateral beam spot spacings are used to help characterize complex multilayer samples. In the preferred embodiment, a spectrometer is also included to provide additional data for characterizing the sample.

US Patent:

6455550, Sep 24, 2002

Filed:

Aug 21, 1998

Appl. No.:

09/138353

Inventors:

Li Chen - Westfield NJ
Robert William Guthrie - Saddle Brook NJ
Jefferson Wright Tilley - North Caldwell NJ
Kenneth Gregory Hull - Cambridge MA

Assignee:

Hoffmann-La Roche Inc. - Nutley NJ

International Classification:

A61K 314166

US Classification:

514341, 514386, 5462744, 5483225, 5483255

Abstract:

Compounds of the formula: are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expressing VLA-4.

US Patent:

6522413, Feb 18, 2003

Filed:

Mar 15, 2002

Appl. No.:

10/098641

Inventors:

Jon Opsal - Livermore CA
Li Chen - Fremont CA

Assignee:

Therma-Wave, Inc. - Fremont CA

International Classification:

G01B 1124

US Classification:

356601, 356364, 356369

Abstract:

An apparatus for characterizing multilayer samples is disclosed. An intensity modulated pump beam is focused onto the sample surface to periodically excite the sample. A probe beam is focused onto the sample surface within the periodically excited area. The power of the reflected probe beam is measured by a photodetector. The output of the photodetector is filtered and processed to derive the modulated optical reflectivity of the sample. Measurements are taken at a plurality of pump beam modulation frequencies. In addition, measurements are taken as the lateral separation between the pump and probe beam spots on the sample surface is varied. The measurements at multiple modulation frequencies and at different lateral beam spot spacings are used to help characterize complex multilayer samples. In the preferred embodiment, a spectrometer is also included to provide additional data for characterizing the sample.

US Patent:

6558733, May 6, 2003

Filed:

Oct 26, 2000

Appl. No.:

09/697104

Inventors:

Syed F. A. Hossainy - Fremont CA
Li Chen - San Jose CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

B05D 132

US Classification:

427 224, 427 21, 427 228, 427534, 427555, 427556, 427554, 427154, 427155, 427156, 427282, 427287, 427271, 427272, 427273, 427300, 427307, 216 8, 216 9, 216 10, 216 41, 216 44, 216 45, 216 56, 216 94, 216106, 216108, 216109

Abstract:

An implantable prosthesis, for example a stent, is provided having one or more micropatterned microdepots formed in the stent. Depots are formed in the prosthesis via chemical etching and laser fabrication methods, including combinations thereof. They are formed at preselected locations on the body of the prosthesis and have a preselected depth, size, and shape. The depots can have various shapes including a cylindrical, a conical or an inverted-conical shape. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots.

US Patent:

6560321, May 6, 2003

Filed:

Sep 27, 1999

Appl. No.:

09/405581

Inventors:

Li Chen - Stanford CA
Keith Chu - Laguna Niguel CA

Assignee:

Conexant Systems, Inc. - Newport Beach CA

International Classification:

H04M 1100

US Classification:

37910017, 37910001, 370292, 375222

Abstract:

A half-duplex facsimile modem system according to the present invention may exhibit a shorter startup time relative to conventional systems. The modem system exchanges capabilities information concurrently with the transmission of a conventional answer signal, thus obviating the need for performing a separate capabilities exchange procedure. In addition, the modem system is capable of determining a preferred training sequence duration based upon one or more characteristics of the current channel. The preferred training sequence duration is communicated from the answer modem to the calling modem such that the calling modem can format the training sequence in an appropriate manner. The resultant training sequence has a time duration that is variable in response to, e. g. , the signal-to-noise ratio of the instant channel. These techniques can result in a significant reduction in the startup latency typically associated with conventional half-duplex facsimile modem systems.

US Patent:

6563977, May 13, 2003

Filed:

Jun 27, 2000

Appl. No.:

09/605523

Inventors:

Li Chen - Fremont CA
Shu Zhang - Fremont CA
Wei Yang - Fremont CA

Assignee:

Bayspec, Inc. - Fremont CA

International Classification:

G02B 628

US Classification:

385 24, 385 31, 385 33, 359115, 359122

Abstract:

An optical multiplexing and demultiplexing device includes: a fiber mounting means for securing a plurality of optical fibers each terminating in a fiber end, at least one of the fiber ends radiating a corresponding input beam having a polarization state defined by a polarization plane that may vary as a function of time, and at least one of the fiber ends for receiving an output beam; collimating and focusing means having a focal length, and providing collimation of the input beams, and focusing of the output beams; diffraction means including at least one diffractive element providing for dispersion of optical beams passing therethrough, each diffractive element having an associated diffraction efficiency that varies as a function of the polarization state of light beams passing therethrough; and a polarization rotating means for rotating the plane of polarization of a beam passing therethrough by a specified number of degrees. The device provides for a particular input beam having a first polarization state to be diffracted by the diffractive elements in accordance with a first diffraction efficiency based on the first polarization state. The beam is then passed through the polarization rotating means at least once and thereby rotated into a second polarization state.