Michael Bolger - Los Alamitos CA Kelvin W. Gee - Hacienda Heights CA Nancy C. Lan - S. Pasadena CA Delia Belelli - Rowland Heights CA Seid Mirsadeghi - Sherman Oaks CA Robert Purdy - San Antonio TX
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 3158 A61K 3156 C07J 4300 C07J 4100
US Classification:
514176
Abstract:
Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex.
Method, Compositions, And Compounds For Modulating Brain Excitability
Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-ammobutyric acid/benzodiazepine receptor-chloride ionpore (GBR) complex.
Method For Making 3.Alpha.-Hydroxy, 3.Beta.-Substituted-Pregnanes
Hasan Tahir - Pasadena CA Michael Bolger - Los Alamitos CA Richard Buswell - Santa Rosa CA Richard Gabriel - Woburn MA Jay Stearns - Santa Rosa CA
Assignee:
Cocensys Inc. - Irvine CA
International Classification:
C07J 2100 C07J 4300 C07J 4100
US Classification:
552609
Abstract:
This invention provides a simplified method for converting pregnan-3,20-dione compounds to 3. alpha. -hydroxy,3. beta. -substituted-pregnanes. By selective use of reagents the unprotected dione is converted chemoselectively and diastereoselectively into a 3(R)-pregnan-3-spiro-2'oxirane-20-one intermediate. This intermediate can then be converted regioselectively by a second set of reactions to the 3. alpha. -hydroxy,3. beta. -substituted-20-one form, which can be further modified at the 20-keto position. Through this method, each ketone group is independently treated. By modifying the ketones one at a time, one can obtain the desired stereo-specificity at each site.
Methods, Compositions, And Compounds For Allosteric Modulation Of The Gaba Receptor By Members Of The Androstane And Pregnane Series
Michael B. Bolger - Los Alamitos CA Kelvin W. Gee - Irvine CA Nancy C. Lan - South Pasadena CA Robert H. Purdy - La Jolla CA Seid Mirsadeghi - Rolling Hills CA Syed Hasan Tahir - Edmonton, CA Delia Belelli - Kingsbarns by St. Andrews, GB6
Assignee:
University of Southern California - Los Angeles CA
International Classification:
C07J 900 C07J 2100 C07J 4300 A61K 3158 A61K 3156
US Classification:
514172
Abstract:
Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex.
Method, Compositions, And Compounds For Modulating Brain Excitability
Kelvin W. Gee - Hacienda Heights CA Michael B. Bolger - Los Alamitos CA Roberta E. Brinton - New York NY Deborah J. Burke - Hacienda Heights CA Bruce S. McEwen - Englewood NJ
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 3158 A61K 3156 C07J 4300 C07J 4100
US Classification:
514172
Abstract:
Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-ammobutyric acid/benzodiazepine receptor-chloride ionophore (GBR) complex.
Method, Compositions, And Compounds For Modulating Brain Excitability
Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-ammobutyric acid/benzodiazepine receptor-chloride ionpore (GBR) complex.
Missouri Baptist Cancer Center 3844 S Lindbergh Blvd STE 130, Saint Louis, MO 63127 (314)5250550 (phone), (314)5250551 (fax)
Midwest Oncology & Hematology 3015 N Ballas Rd, Saint Louis, MO 63131 (314)9965169 (phone), (314)9964679 (fax)
Education:
Medical School Washington University School of Medicine Graduated: 1981
Procedures:
Bone Marrow Biopsy Chemotherapy
Conditions:
Lung Cancer Non-Hodgkin's Lymphoma Pancreatic Cancer Anemia Gastric Cancer
Languages:
English
Description:
Dr. Bolger graduated from the Washington University School of Medicine in 1981. He works in Saint Louis, MO and 1 other location and specializes in Hematology/Oncology and Internal Medicine. Dr. Bolger is affiliated with Missouri Baptist Medical Center.
Name / Title
Company / Classification
Phones & Addresses
Michael J. Bolger President
M. T. PATRICK CONSTRUCTION CO
3004 Verdugo Rd, Los Angeles, CA 90065
Michael J. Bolger President
WM. S. BRIAN CONST. CO., INC
3004 Verdugo Rd, Los Angeles, CA 90065
Michael J. Bolger Manager
Michael B, LLC Business Services at Non-Commercial Site
710 3 St, San Diego, CA 92118
Michael Bolger Treasurer, Director, Secretary
The Arc Group, Inc.-Illinois
Michael J. Bolger
Michael B. Gourmet Foods, LLC Food Services
695 Town Ctr Dr, Costa Mesa, CA 92626 3907 W Verdugo Ave, Burbank, CA 91505
Onefinestay Aug 2017 - May 2018
U.s Expansion Specialist
Travel Keys Dec 2016 - Aug 2017
Sales and Marketing Specialist
Boutique-Homes.com May 2016 - Dec 2016
Business Development
Driftr May 2016 - Dec 2016
Advisory Board Member
Globe Homes Llc Feb 2016 - May 2016
Business Development Associate
Skills:
Marketing Sales Public Speaking Online Advertising Management Tourism Entrepreneurship Marketing Strategy Business Development Strategy Social Media Marketing Event Management Social Media
Officials identified the six people who were killed in Madison County as Melissa Bazley, 63; Rodney Clark, 64; Cecilia Lloyd, 72; Michael Bolger, 37; Kinlee Bolger, 5; and Owen Bolger, 2. The victims came from three different households.