Michael J Hauser

US Patent:

6451596, Sep 17, 2002

Filed:

May 2, 2000

Appl. No.:

09/562919

Inventors:

Jeffrey S. Chamberlain - Seattle WA
Andrea Amalfitano - Durham NC
Michael A. Hauser - Milan MI
Rajendra Kumar-Singh - Los Angeles CA

Assignee:

Regents of the University of Michigan - Ann Arbor MI

International Classification:

C12N 1586

US Classification:

435325, 4352351, 4353201, 435456, 536 231, 536 241

Abstract:

The present invention provides improved adenovirus vectors and packaging cell lines. One type of improved adenoviral vector comprises deletions within the E2b region of the adenoviral genome. These E2b-deleted virus are used in conjunction with novel cell lines that constitutively express E2b gene products. The present invention further provides adenoviral vectors deleted for all viral coding regions. These âguttedâ vectors permit the transfer of large genes to cells as demonstrated herein by the transfer of the dystrophin gene to the muscle of mice. The E2b-deleted vectors and the gutted vectors provide improved adenoviral vectors useful for a wide variety of gene therapy applications.

US Patent:

20140032135, Jan 30, 2014

Filed:

Apr 9, 2012

Appl. No.:

13/442062

Inventors:

ETHAN H. CANNON - SAMMAMISH WA, US
MICHAEL J. HAUSER - BOLTON VT, US
TIMOTHY D. SULLIVAN - UNDERHILL VT, US

Assignee:

INTERNATIONAL BUSINESS MACHINES CORPORATION - ARMONK NY

International Classification:

G01T 5/02

US Classification:

702 36, 257 48

Abstract:

Systems and methods to ensure correct operation of a semiconductor chip in the presence of ionizing radiation is disclosed. The system includes a semiconductor chip, a first radiation detection array incorporated in the semiconductor chip, and at least one additional radiation detection array incorporated in the semiconductor chip. a processor determines a region of the semiconductor chip affected by an incident radiation particle by analyzing a trajectory of the radiation particle determined from locations of sensors hit by the radiation particle in the first radiation detection array and the at least one additional radiation detection array. The processor determines whether corrective action is needed based on the region of the semiconductor chip affected by the incident radiation particle.

US Patent:

20160018677, Jan 21, 2016

Filed:

Jul 16, 2014

Appl. No.:

14/332886

Inventors:

- Armonk NY, US
William M. GREEN - Astoria NY, US
Michael J. HAUSER - Bolton VT, US
Edward W. KIEWRA - South Burlington VT, US
Xuefeng LIU - Roseville CA, US
Steven M. SHANK - Jericho VT, US

International Classification:

G02F 1/025
H01L 29/10
H01L 29/08
H01L 29/423
H01L 29/40
G02B 6/136
H01L 29/49
H01L 27/088
H01L 21/306
H01L 29/66
H01L 27/06
H01L 29/78
H01L 29/06

Abstract:

A device includes a laterally diffused metal-oxide-semiconductor (LDMOS) device integrated with an optical modulator. An optical waveguide of the optical modulator includes a silicon-containing structure in a drift region of the LDMOS device.

US Patent:

20150316195, Nov 5, 2015

Filed:

Apr 30, 2015

Appl. No.:

14/700288

Inventors:

- Hauppauge NY, US
Robert E. Kodadek - Long Beach NY, US
Michael Passaretti - Smithtown NY, US
Michael Hauser - East Rockaway NY, US
Eric S. Feldman - Glen Head NY, US
Benjamin Lagosz-Sinclair - Brooklyn NY, US

International Classification:

F16L 55/32

Abstract:

A system and method for pipeline maintenance may include a payload and a transport module having the payload attached thereto. The transport module may include a plurality of movable arms each having at least one respective wheel. At least some of the wheels may be drive wheels which are operable in a first orientation to drive the transport module linearly along a length of a pipeline, and are further operable in a second orientation to drive the transport module circumferentially around an inner surface of the pipeline. At least some of the arms are operable to move the payload in a generally radial direction toward and away from an interior surface of the pipeline.