Michael D Leach

US Patent:

7077339, Jul 18, 2006

Filed:

Feb 3, 2003

Appl. No.:

10/357056

Inventors:

Michael D Leach - Warsaw IN, US

Assignee:

Biomet, Inc. - Warsaw IN

International Classification:

B05B 7/12

US Classification:

239417, 239418, 2394175, 222137, 222327, 2221455, 604191

Abstract:

An applicator for applying a multi-component bio-material including at least two containers. Both containers are held in a structure or oriented in a structure such that material contained in the containers can be expressed from oriented outlets simultaneously. The applicator includes a graspable member which allows the material to be expressed from all containers of the applicator substantially simultaneously. The applicator may be constructed such that a pre-selected and substantially different volume is expressed from each of the containers substantially simultaneously.

US Patent:

7179391, Feb 20, 2007

Filed:

May 23, 2003

Appl. No.:

10/445381

Inventors:

Michael Leach - Warsaw IN, US
Joel Higgins - Claypool IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

B01D 17/038
B01D 21/26
B04B 1/02

US Classification:

210782, 210781, 210789, 2103801, 604 601, 604218, 604403, 494 37, 494 43, 494 50, 422 72, 422101

Abstract:

An apparatus that allows for separating and collecting a concentrated fraction of a fluid, such as a whole blood sample, adipose tissue, or a bone marrow sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. The apparatus includes a container to be placed to a centrifuge after being filled with a whole blood sample. A buoy or fraction separator, which has a density less than that of red blood cells of a whole blood sample, is disposed in the container. During the centrifuge process the buoy separates the red blood cells from another fraction of the whole blood. After the centrifuge process is finished a plunger is used to produce at least two other fractions, including a plasma fraction and a buffy coat. Then, the buffy coat may be removed from the container without commingling the fractions of the sample.

US Patent:

7374678, May 20, 2008

Filed:

Sep 2, 2004

Appl. No.:

10/932882

Inventors:

Michael Leach - Warsaw IN, US
Joel C. Higgins - Claypool IN, US
Brandon Miller - Rochester IN, US

Assignee:

Biomet Biologics, Inc. - Warsaw IN

International Classification:

B01D 17/038
B01D 21/26
B04B 1/02

US Classification:

2103801, 210782, 210789, 2103601, 210516, 422 72, 422101, 494 43, 494 50, 494 67, 604 601, 604 605, 604 615, 604218, 604403

Abstract:

An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.

US Patent:

7553413, Jun 30, 2009

Filed:

Jan 30, 2006

Appl. No.:

11/342982

Inventors:

Randel Dorian - San Diego CA, US
Michael D. Leach - Warsaw IN, US
Richard Wood Storrs - Berkeley CA, US

Assignee:

Hanuman LLC - San Francisco CA
Biomet Biologics, LLC - Warsaw IN

International Classification:

B01D 15/02
B01D 24/00
B01D 29/00

US Classification:

210219, 210295, 2105021, 422 44, 422102, 436177, 436178

Abstract:

A plasma concentrator of this invention having a concentrator chamber, concentrator gel beads, a filter, and an agitator. The agitator has agitator blades extending outwardly from the lower end. The agitator end is positioned in the concentrator chamber and supported for rotation about its central axis and for reciprocal movement along its central axis. The concentrator has a top with an upper opening through which the upper end of the actuator stem extends, and a lower opening in which the filter is positioned. The concentrator chamber can have a cylindrical inner wall, and the agitator blades can have an outer edge in close proximity to the inner wall with the space between the outer edge and the inner wall being less than the diameter of the gel beads. The filter is selected to block effective flow of plasma therethrough under ambient gravity conditions and permit plasma and plasma concentrate flow therethrough under centrifugal forces of the separation gravity. The method concentrates plasma by removing water without significantly denaturing the fibrinogen in the plasma.

US Patent:

7670384, Mar 2, 2010

Filed:

Apr 19, 2006

Appl. No.:

11/407409

Inventors:

Mukesh Kumar - Warsaw IN, US
Ned M. Hamman - Leesburg IN, US
Michael D. Leach - Warsaw IN, US
John Manocchio - Paramus NJ, US
Paul D'Antonio - Morristown NJ, US
Daryl L. Carter - Hopatcong NJ, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

A61F 2/28
A61K 35/32

US Classification:

623 2363, 623 2351, 623 2356, 424549

Abstract:

Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are provided for making formed compositions for application to a bone surface of a human or animal subject comprise mixing a demineralized bone and water; heating the mixture to form a carrier; mixing the carrier with bone to form a moldable composition; and molding the moldable composition to produce a formed composition. Several apparatuses are provided in which to hydrate the formed bone composition. Methods of hydrating a formed bone composition are also provided.

US Patent:

7694828, Apr 13, 2010

Filed:

Apr 27, 2005

Appl. No.:

11/116153

Inventors:

Matthew J Swift - Fort Wayne IN, US
Barry F Hecker - Pierceton IN, US
Michael D Leach - Warsaw IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

B01D 21/26
B01D 33/01

US Classification:

2105123, 210782, 210358, 210173, 2105121, 2105122, 2103601, 2103602, 210210, 210208, 210781, 366220, 366241, 604 601, 604218, 604403, 494 37, 494 43, 494 50, 422 72, 422101

Abstract:

A method and apparatus for obtaining various components of a multi-component material. Generally, a component of a whole blood sample may be concentrated from a patient and re-introduced to the same patient. For example, a clotting component, such as thrombin, from a whole blood sample may be extracted and concentrated in an apparatus and collection to be reapplied or reintroduced into a patient.

US Patent:

7708152, May 4, 2010

Filed:

Jan 30, 2006

Appl. No.:

11/342761

Inventors:

Randel Dorian - San Diego CA, US
Michael D. Leach - Warsaw IN, US

Assignee:

Hanuman LLC - San Francisco CA
Biomet Biologics, LLC - Warsaw IN

International Classification:

B01D 21/26
B04B 7/08

US Classification:

2105123, 210319, 210294, 21032168, 21032187, 2103801, 210787, 2103601, 2105121, 494 35, 494 37

Abstract:

The PRP separator-concentrator of this invention is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly, and a concentrator assembly. The centrifugal separator assembly comprises a centrifugal drum separator that includes an erythrocyte capture module and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate. The centrifugal drum separator has an erythrocyte trap. The water removal module can be a syringe device with water absorbing beads or it can be a pump-hollow fiber cartridge assembly. The hollow fibers are membranes with pores that allow the flow of water through the fiber membrane while excluding flow of clotting factors useful for sealing and adhering tissue and growth factors helpful for healing while avoiding activation of platelets and disruption of any trace erythrocytes present in the PRP.

US Patent:

7766900, Aug 3, 2010

Filed:

Sep 8, 2005

Appl. No.:

11/222303

Inventors:

Michael D Leach - Warsaw IN, US
Barry F Hecker - Pierceton IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

A61M 1/00
A61M 5/315
A61M 35/00
A61M 37/00

US Classification:

604540, 604218, 604289, 604290, 604310, 604311, 604 501, 604 615

Abstract:

A method and apparatus for separation, concentration, and/or applying a biological or bio-engineered fluid. Generally, the fluid application device includes a sprayer body to enable the application of the fluid and a container adaptable to enable the separation of the fluid into at least a first component and a second component. The container is releasably coupled to the nozzle. The nozzle is adapted to withdraw at least one of the first component or the second component from the container after the fluid has been separated to apply the fluid to a selected site.