Michael A Leach

US Patent:

7077339, Jul 18, 2006

Filed:

Feb 3, 2003

Appl. No.:

10/357056

Inventors:

Michael D Leach - Warsaw IN, US

Assignee:

Biomet, Inc. - Warsaw IN

International Classification:

B05B 7/12

US Classification:

239417, 239418, 2394175, 222137, 222327, 2221455, 604191

Abstract:

An applicator for applying a multi-component bio-material including at least two containers. Both containers are held in a structure or oriented in a structure such that material contained in the containers can be expressed from oriented outlets simultaneously. The applicator includes a graspable member which allows the material to be expressed from all containers of the applicator substantially simultaneously. The applicator may be constructed such that a pre-selected and substantially different volume is expressed from each of the containers substantially simultaneously.

US Patent:

7179391, Feb 20, 2007

Filed:

May 23, 2003

Appl. No.:

10/445381

Inventors:

Michael Leach - Warsaw IN, US
Joel Higgins - Claypool IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

B01D 17/038
B01D 21/26
B04B 1/02

US Classification:

210782, 210781, 210789, 2103801, 604 601, 604218, 604403, 494 37, 494 43, 494 50, 422 72, 422101

Abstract:

An apparatus that allows for separating and collecting a concentrated fraction of a fluid, such as a whole blood sample, adipose tissue, or a bone marrow sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. The apparatus includes a container to be placed to a centrifuge after being filled with a whole blood sample. A buoy or fraction separator, which has a density less than that of red blood cells of a whole blood sample, is disposed in the container. During the centrifuge process the buoy separates the red blood cells from another fraction of the whole blood. After the centrifuge process is finished a plunger is used to produce at least two other fractions, including a plasma fraction and a buffy coat. Then, the buffy coat may be removed from the container without commingling the fractions of the sample.

US Patent:

7374678, May 20, 2008

Filed:

Sep 2, 2004

Appl. No.:

10/932882

Inventors:

Michael Leach - Warsaw IN, US
Joel C. Higgins - Claypool IN, US
Brandon Miller - Rochester IN, US

Assignee:

Biomet Biologics, Inc. - Warsaw IN

International Classification:

B01D 17/038
B01D 21/26
B04B 1/02

US Classification:

2103801, 210782, 210789, 2103601, 210516, 422 72, 422101, 494 43, 494 50, 494 67, 604 601, 604 605, 604 615, 604218, 604403

Abstract:

An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.

US Patent:

7670384, Mar 2, 2010

Filed:

Apr 19, 2006

Appl. No.:

11/407409

Inventors:

Mukesh Kumar - Warsaw IN, US
Ned M. Hamman - Leesburg IN, US
Michael D. Leach - Warsaw IN, US
John Manocchio - Paramus NJ, US
Paul D'Antonio - Morristown NJ, US
Daryl L. Carter - Hopatcong NJ, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

A61F 2/28
A61K 35/32

US Classification:

623 2363, 623 2351, 623 2356, 424549

Abstract:

Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are provided for making formed compositions for application to a bone surface of a human or animal subject comprise mixing a demineralized bone and water; heating the mixture to form a carrier; mixing the carrier with bone to form a moldable composition; and molding the moldable composition to produce a formed composition. Several apparatuses are provided in which to hydrate the formed bone composition. Methods of hydrating a formed bone composition are also provided.

US Patent:

7766900, Aug 3, 2010

Filed:

Sep 8, 2005

Appl. No.:

11/222303

Inventors:

Michael D Leach - Warsaw IN, US
Barry F Hecker - Pierceton IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

A61M 1/00
A61M 5/315
A61M 35/00
A61M 37/00

US Classification:

604540, 604218, 604289, 604290, 604310, 604311, 604 501, 604 615

Abstract:

A method and apparatus for separation, concentration, and/or applying a biological or bio-engineered fluid. Generally, the fluid application device includes a sprayer body to enable the application of the fluid and a container adaptable to enable the separation of the fluid into at least a first component and a second component. The container is releasably coupled to the nozzle. The nozzle is adapted to withdraw at least one of the first component or the second component from the container after the fluid has been separated to apply the fluid to a selected site.

US Patent:

7771590, Aug 10, 2010

Filed:

Aug 23, 2005

Appl. No.:

11/210005

Inventors:

Michael D. Leach - Warsaw IN, US
James M. McKale - Syracuse IN, US

Assignee:

Biomet Manufacturing Corp. - Warsaw IN

International Classification:

B04B 5/02

US Classification:

210109, 210782, 210789, 210515, 210516, 210518, 422 72, 422101, 422102, 494 16, 494 19

Abstract:

A method and apparatus for separating and concentrating a selected component from a multi-component material. The multi-component material may include a whole sample such as adipose tissue, whole blood, or the like. The apparatus generally includes a moveable piston positioned within a separation container and a withdrawal tube that is operable to interact with a distal end of the collection container past the piston. Material can be withdrawn through the withdrawal tube.

US Patent:

7806276, Oct 5, 2010

Filed:

Apr 11, 2008

Appl. No.:

12/101594

Inventors:

Michael D. Leach - Warsaw IN, US
Randel Dorian - San Diego CA, US
Jacy C. Hoeppner - Warsaw IN, US

Assignee:

Hanuman, LLC - San Francisco CA
Biomet Biologics, LLC - Warsaw IN

International Classification:

B01D 21/26
B01D 17/02
B01D 17/038
C02F 1/38

US Classification:

210516, 2102421, 210513, 210515, 210518, 422101

Abstract:

A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.

US Patent:

7832566, Nov 16, 2010

Filed:

May 25, 2006

Appl. No.:

11/441275

Inventors:

Michael D. Leach - Warsaw IN, US
Joel C. Higgins - Claypool IN, US
Matthew Swift - Fort Wayne IN, US
Nathan Gordon - Plymouth IN, US

Assignee:

Biomet Biologics, LLC - Warsaw IN

International Classification:

B01D 21/26

US Classification:

2103801, 210782, 210789, 2103601, 210516, 422 72, 422101, 494 43, 494 50, 494 67, 604 601, 604 605, 604 615, 604218, 604403

Abstract:

An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.