Michael S Roark

US Patent:

56630557, Sep 2, 1997

Filed:

Dec 13, 1994

Appl. No.:

8/354914

Inventors:

Gregory A. Turner - Independence MO
James F. Maher - Broken Arrow OK
C. Worth Clinkscales - Tulsa OK
Michael D. Roark - Owasso OK

Assignee:

Oklahoma Medical Research Foundation - Oklahoma City OK

International Classification:

C12Q 134
C12Q 170
C12N 926

US Classification:

435 18

Abstract:

Chromogenic derivatives of N-acetylneuraminic acid modified in the 4-position to contain a hydrogen atom, a fluorine atom, a methoxy group, or an ethoxy group are used as substrates in colorimetric assays for human influenza neuraminidase activity in clinical specimens for the purpose of selectively diagnosing influenza infection. The substrates may exhibit different reactivity with the different types of influenza neuraminidases, thus enabling one to discern the specific type of influenza infection and prescribe appropriate treatment and/or supportive therapy therefor.

US Patent:

20070151797, Jul 5, 2007

Filed:

May 28, 2003

Appl. No.:

10/558324

Inventors:

Michael Roark - Lee's Summit MO, US
Mark Boe - Reno NV, US
Werner Hoelmer - Hamilton OH, US
Joop Gooden - Steenwijk, NL
Gerold Valk - Vlaardingen, NL
Rene Parchen - Schiedam, NL
Barie Brettmann - Overland Park KS, US

International Classification:

B64F 1/26

US Classification:

181210000

Abstract:

A ground run up enclosure () which comprises an air inlet structure (), a test chamber (), an acoustic enclosure () and a main enclosure door (). The air inlet structure () is adapted to receive ambient air and redirect it into the test chamber (). The test chamber () is designed to receive a portion of an aircraft () therein. The acoustic enclosure () receives the airflow from the test chamber (). The airflow continues through the acoustic enclosure () until it contacts a front surface of the main enclosure door () and is redirected upward and out of the enclosure.