Alfredo M. Morales - Livermore CA Michael R. Winter - Goleta CA Linda A. Domeier - Danville CA Shawn M. Allan - Henrietta NY Dawn M. Skala - Fremont CA
Assignee:
Sandia Corporation - Livermore CA
International Classification:
C08K 308
US Classification:
524439, 524440, 524441, 419 38, 419 39, 419 42
Abstract:
A method is provided for fabricating metallic microstructures, i. e. , microcomponents of micron or submicron dimensions. A molding composition is prepared containing an optional binder and nanometer size (1 to 1000 nm in diameter) metallic particles. A mold, such as a lithographically patterned mold, preferably a LIGA or a negative photoresist mold, is filled with the molding composition and compressed. The resulting microstructures are then removed from the mold and the resulting metallic microstructures so provided are then sintered.
Will Wright - Orinda CA, US Michael Winter - Orinda CA, US Matthew Sibigtroth - Berkeley CA, US
Assignee:
Stupid Fun Club, LLC - Berkeley CA
International Classification:
A63H 29/22
US Classification:
446484, 446297, 446397
Abstract:
The invention provides a method for figurines to form and join a network of figurines by setting them near other figurines, by activating them via a power switch, or by placing them in communication with a central hub. A communications path using radio or IR frequency is used to form the network, such that only one figurine can transmit data while the others receive data at any time. Once the network has been formed, the figurines can formulate behaviors based on the attributes, requests, and actions of the others. These behaviors are based on the data transpired between the figurines and can include meaning of spoken words, current state, etc. Each figurine has a personality controlled by its internal data, which also controls its relationships with others. Each figurine can spontaneously create a speech or action based on the reply given by another coupled with data stored within its databank.
Will Wright - Orinda CA, US Michael Winter - Orinda CA, US Matthew Sibigtroth - Berkeley CA, US
International Classification:
A63H 3/28
US Classification:
446297000, 446484000
Abstract:
The invention provides a method for figurines to form and join a network of figurines by setting them near other figurines, by activating them via a power switch, or by placing them in communication with a central hub. A communications path using radio or IR frequency is used to form the network, such that only one figurine can transmit data while the others receive data at any time. Once the network has been formed, the figurines can formulate behaviors based on the attributes, requests, and actions of the others. These behaviors are based on the data transpired between the figurines and can include meaning of spoken words, current state, etc. Each figurine has a personality controlled by its internal data, which also controls its relationships with others. Each figurine can spontaneously create a speech or action based on the reply given by another coupled with data stored within its databank.
Heme-Binding Photoactive Polypeptides And Methods Of Use Thereof
Michael A. Marletta - Berkeley CA, US Michael B. Winter - Berkeley CA, US Emily J. McLaurin - Seattle MA, US Steven Y. Reece - Cambridge MA, US Charles Olea, JR. - San Diego CA, US Daniel G. Nocera - Winchester MA, US
The present disclosure provides photoactive polypeptides. A subject photoactive polypeptide is useful in a variety of applications, which are also provided.
Matrix Metalloprotease-Cleavable And Serine Or Cysteine Protease-Cleavable Substrates And Methods Of Use Thereof
- South San Francisco CA, US Michael B. WINTER - San Francisco CA, US
International Classification:
C07K 16/28 A61P 35/00
Abstract:
The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a substrate for at least one matrix metalloprotease (MMP) and at least a second cleavable moiety (CM2) that is a substrate for at least one serine protease (SP) or at least one cysteine protease (CP), to activatable antibodies and other larger molecules that include these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease or at least one cysteine protease (CP), and to methods of making and using these polypeptides that include at least a CM1 that is a substrate for at least one MMP protease and at least a CM2 that is a substrate for at least one SP protease or at least one cysteine protease (CP) in a variety of therapeutic, diagnostic and prophylactic indications.
Systems And Compositions For Diagnosing Pathogenic Fungal Infection And Methods Of Using The Same
- Oakland CA, US Michael Winter - Oakland CA, US Charles Craik - Oakland CA, US Alexander Johnson - Oakland CA, US Anthony O'Donoghue - Oakland CA, US
International Classification:
G01N 33/569 C07K 14/40 C12N 9/60
Abstract:
The present disclosure relates generally to detection of contamination of a sample or diagnosis of subject based upon detection or quantification of amino acid sequences in a sample, specifically to the identification and use of molecular biomarkers for biofilm infections.
Jan 2012 to 2000 Postdoctoral FellowUniversity of California, Berkeley Berkeley, CA Aug 2006 to Dec 2011 Graduate Student Researcher
Education:
University of California, Berkeley Berkeley, CA 2006 to 2011 Ph.D. in ChemistryKalamazoo College Kalamazoo, MI 2002 to 2006 B.A. in Chemistry
Skills:
- Proteomics: peptide sequencing with LC-MS/MS (Thermo LTQ-FT, LTQ-Orbitrap XL)<br/>- Enzymatic Activity Assays: mass spectrometry, fluorogenic substrates, HPLC, and ELISA<br/>- Recombinant Protein Expression: bacterial (E. coli), insect cell (Sf9), and yeast (Pichia) systems<br/>- Recombinant Protein Purification: FPLC (GE AKTA and Bio-Rad BioLogic systems)<br/>- HPLC: small molecule and peptide separations (Agilent 1100/1200 and Waters nanoAQUITY)<br/>- Peptide Synthesis: solid-phase synthesis of unmodified and fluorogenic peptides<br/>- Molecular Biology Techniques: DNA isolation, PCR, mutagenesis, transformation, and transfection<br/>- Mammalian Cell Culture: propagation and maintenance of cancer cell lines<br/>- Protein Crystallization: automated screening and hit optimization
MacLeod reported from Beijing, Maresca from Ho Chi Minh City, Vietnam. Contributing: Kim Hjelmgaard in London, Melanie Eversley in New York, Donna Leinwand Leger in Washington, Allison Gray, Doyle Rice and Gary Strauss in McLean, Va., Michael Winter in Oakland; the Associated Press.
Hot at Guantanamo: Fifty Shades of Grey is "mommy porn" no more. E.L. James' erotic books starring Christian Grey and Anastasia Steele are the most requested books from prison library by "high value" terrorism suspects confined at Guantanamo Bay, USA TODAY's Michael Winter reports.
Date: Jul 31, 2013
Category: Entertainment
Source: Google
The Women Mistaken for Chris Dorner Will Get 4x Ransom Cash
told Southern California residents to be on the lookout for a charcoal Nissan Titan pickup truck.Carranza and Emma, who were delivering newspapers early in the Torrance that Thursdayin theirblue Toyota Tacomawere shot at with at least 100 rounds of ammo, USA Today's Michael Winter reports.It wa
Los Angeles (written by Michael Winter/USA Today) -- The man identified as the producer of an Internet film that sparked violent protests across the Muslim world has been arrested in Los Angeles for violating probation for a 2010 bank fraud conviction.
Washington, DC (written by Michael Winter/USA Today) -- The Obama administration is bolstering the U.S. presence in the Persian Gulf by building a secret missile-defense radar station in Qatar, sending an additional aircraft carrier and preparing for its biggest minesweeping exercises in the region,
The other loan made that day was a $26.9 million loan to former Chicago banker and later real estate developer Michael Winter and associate Judi Fishman to buy and restore an apartment building in Los Angeles. Within a few months after the bank renewed the loan in August 2009, the borrowers defaulte