Vincent C. Bond - Stone Mountain GA, US James Lillard - Smyrna GA, US Ming Bo Huang - Atlanta GA, US Harvey Bumpers - Stone Mountain GA, US Michael Powell - Douglasville GA, US
Assignee:
Morehouse School of Medicine - Atlanta GA
International Classification:
C07K 4/02
US Classification:
530328, 514 15
Abstract:
The present invention provides a means of selectively killing epithelial cell carcinomas by administering a CXCR4-specific sequence of the Gp120 protein or Nef proteins or the proteins themselves (the modulators) such as that found in strains HIV-1, HIV-2, SIV, or FIV CXCR4-specific Gp 120 sequences or Nef proteins or sequences may be delivered to the mucosa or systemically. The mucosal means of application include oral, intranasal, ocular, intravaginal, rectal, and/or intraurethral administration in liquid or particulate form.
Methods Of Generating A Humoral Immune Response Against Human Immunodeficiency Virus (Hiv) Comprising Administering Nef Apoptotic Motif-Containing Polypeptide-Conjugates
Vincent C. Bond - Stone Mountain GA, US Michael Powel - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Cleve James - Washington DC, US
Assignee:
Morehouse School of Medicine - Atlanta GA
International Classification:
A61K 39/21 A61K 39/385
US Classification:
4241881, 4242081, 42419611
Abstract:
A small peptide of 10 or 11 mers, when linked to an immunogenic moiety, can protect against naferious effects of Nef protein of HIV. The vaccine is not used to induce sterilizing immunity, but to block the ability of soluble Nef protein to induce apoptosis, and to therefore alleviate lymphocyte depletion and organ damage.
Tumor Cytotoxicity Induced By Modulators Of The Cxcr4 Receptor
Vincent C. Bond - Stn Mtn. GA, US James W. Lillard - Smyrna GA, US Ming Bo Huang - Atlanta GA, US Harvey Bumpers - Stone Mountain GA, US Michael Powell - Douglasville GA, US
The present invention provides a means of selectively killing epithelial cell carcinomas by administering a CXCR4-specific sequence of the Gp120 protein or Nef proteins or the proteins themselves (the modulators) such as that found in strains HIV-1, HIV-2, SIV, or FIV CXCR4-specific Gp 120 sequences or Nef proteins or sequences may be delivered to the mucosa or systemically. The mucosal means of application include oral, intranasal, ocular, intravaginal, rectal, and/or intraurethral administration in liquid or particulate form.
Compositions And Methods For Treating Aids Or Cancer By Inhibiting The Secretion Of Microparticles
Vincent Craig Bond - Stone Mountain GA, US Michael Powell - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Syed Ali - Atlanta GA, US Andrea D. Raymond - Atlanta GA, US Martin Neville Shelton - Stone Mountain GA, US Francois Jean Villinger - Decatur GA, US
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
Compositions And Methods For Treating Cancer By Inhibiting The Secretion Of Microparticles
Vincent Craig Bond - Stone Mountain GA, US Michael Powell - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Syed Ali - Pinang, MY Andrea D. Raymond - Atlanta GA, US Martin Neville Shelton - Stone Mountain GA, US Francois Jean Villinger - Decatur GA, US
Novel peptides that inhibit the release of microparticles from cells are disclosed. Also disclosed are polynucleotides encoding the peptides, expression vectors carrying the polynucleotides and methods for treating tumors using the novel peptides.
Compositions And Methods For Treating Aids Or Cancer By Inhibiting The Secretion Of Microparticles
Vincent Craig Bond - Stone Mountain GA, US Michael Powell - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Syed Ali - Pinang, MY Andrea D. Raymond - Atlanta GA, US Martin Neville Shelton - Stone Mountain GA, US Francois Jean Villinger - Decatur GA, US
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
Compositions And Methods For Treating Aids Or Cancer By Inhibiting The Secretion Of Microparticles
Michael Powell - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Syed Ali - Atlanta GA, US Andrea D. Raymond - Atlanta GA, US Martin Neville Shelton - Stone Mountain GA, US Francois Jean Villinger - Decatur GA, US
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
Antimicrobial Compositions And Methods Of Use Thereof
Vincent Craig Bond - Stone Mountain GA, US Michael Powell - Douglasville GA, US Ming Bo Huang - Atlanta GA, US Syed Ali - Pulau Pinang, MY Martin Neville Shelton - Stone Mountain GA, US
Assignee:
MOREHOUSE SCHOOL OF MEDICINE - Atlanta GA
International Classification:
A61K 35/76 A61P 31/00 A61K 38/08
US Classification:
424 936, 514 23
Abstract:
The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.
Dr. Huang graduated from the Chung Shan Med And Dental Coll, Taiching, Taiwan in 1969. He works in Somerville, NJ and specializes in Family Medicine and Acupuncturist. Dr. Huang is affiliated with Robert Wood Johnson University Hospital Somerset.
Ming N Huang MD 1240 South St, San Gabriel, CA 91776 (626)5765465 (phone), (626)5765826 (fax)
Education:
Medical School Natl Taiwan Univ Coll of Med, Taipei, Taiwan (385 02 Prior 1/71) Graduated: 1968
Procedures:
Pacemaker and Defibrillator Procedures
Languages:
Chinese English
Description:
Dr. Huang graduated from the Natl Taiwan Univ Coll of Med, Taipei, Taiwan (385 02 Prior 1/71) in 1968. He works in San Gabriel, CA and specializes in Vascular Surgery. Dr. Huang is affiliated with Alhambra Hospital Medical Center and Garfield Medical Center.
Stony Brook Radiology PC 101 Nicolls Rd, Stony Brook, NY 11794 (631)4445400 (phone), (631)4447538 (fax)
Education:
Medical School Beijing Med Univ, Beijing City, Beijing, China Graduated: 1995
Languages:
English Spanish
Description:
Dr. Huang graduated from the Beijing Med Univ, Beijing City, Beijing, China in 1995. She works in Stony Brook, NY and specializes in Diagnostic Radiology and Musculoskeletal Radiology. Dr. Huang is affiliated with John T Mather Memorial Hospital, Northport VA Medical Center and Stony Brook University Hospital.
Name / Title
Company / Classification
Phones & Addresses
Ming Jian Huang CEO
CH&DL INC
3330 Cobb Pkwy #15 & 16, Acworth, GA 30101 2733 Fairlane Dr, Atlanta, GA 30340
Ming Huang President
Casual & Co Inc Textiles Woven Nec Whol
160 Passaic Ave, Kearny, NJ 07032 (201)9918400
Ming Huang Senior Information Scientist In The Patent Department
Cold Spring Harbor Laboratory Association Noncommercial Research Organization · Noncommercial Research Organizations, Nsk
1 Bungtown Rd, Cold Spring Harbor, NY 11724 PO Box 100, Cold Spring Harbor, NY 11724 (516)3678446, (516)3678801
Ming Je Huang
INTEGRATIVE CHIROPRACTIC CLINIC, LLC
Ming H Huang
267HUANG EXPRESS INC
138-62B 68 Dr B, Flushing, NY 11367 138 62B 68 Dr B, Flushing, NY 11367
Ming Hui Huang Soc signatory
YI MEI INTERNATIONAL, LLC
Ming B. Huang Director, President, Secretary, Treasurer