Mohammad Aminul Hoque

US Patent:

20100156518, Jun 24, 2010

Filed:

Dec 18, 2008

Appl. No.:

12/338820

Inventors:

Mohammad Rashedul Hoque - Allen TX, US
Ken R. King - Lucas TX, US

International Classification:

G05F 1/10

US Classification:

327538

Abstract:

Various apparatuses, methods and systems for a front end protection circuit with a dynamic charge pump system are disclosed herein. For example, some embodiments provide an apparatus such as a voltage regulator, a current regulator, a driver circuit or a switch protection circuit. The apparatus includes an output switch, a switch controller and a voltage threshold detector. The apparatus operates in a reduced power mode when the threshold detector detects a feedback level passing a threshold. In some particular embodiments, the switch controller includes a charge pump and an oscillator that run at lower speeds to reduce power usage when the feedback level passes the threshold. In various embodiments, the feedback level is a voltage level at the output switch control input, the output voltage from the output switch, or the output current from the output switch.

US Patent:

20120014871, Jan 19, 2012

Filed:

Feb 26, 2010

Appl. No.:

13/203480

Inventors:

Mohammad O. Hoque - Towson MD, US
Mariana Brait - Baltimore MD, US
Leonel Maldonado - Baltimore MD, US

International Classification:

A61K 51/10
A61P 35/00
A61K 31/7068
C12Q 1/68
A61K 31/706

US Classification:

424 149, 435 614, 435 611, 514 43, 514 49

Abstract:

The present invention provides methods and kits for identifying a cell that exhibits or is predisposed to exhibiting unregulated growth by detecting hypermethylation of a gene or a regulatory region in at least one gene in the cell. Also provided are methods for diagnosis or prognosis of ovarian cancer in a subject. Also provided are methods of ameliorating ovarian cancer in a subject by administering to the subject an agent that demethylates a hypermethylated gene or regulatory region thereof.

US Patent:

20200181709, Jun 11, 2020

Filed:

Jun 14, 2016

Appl. No.:

15/737228

Inventors:

- Baltimore MD, US
Leonel Francisco Maldonado Gonzalez - Baltimore MD, US
Mariana Brait Rodrigues De Oliveira - Baltimore MD, US
Mohammad O. Hoque - Towson MD, US

International Classification:

C12Q 1/6886
A61K 31/706
A61K 31/7068
A61K 31/164
A61P 35/00

Abstract:

The invention provides methods for detecting a cellular proliferative disorder (e.g., urothelial cancer) in a subject by assessing the methylation status of the CCND2, CCNA1 or CALCA promoter in a nucleic acid sample. The methods of the invention are useful for diagnostic, prognostic as well therapeutic regimen predictions.

US Patent:

20160273051, Sep 22, 2016

Filed:

Mar 17, 2016

Appl. No.:

15/073337

Inventors:

- Baltimore MD, US
Elisa Guida - Baltimore MD, US
Mohammad Hoque - Baltimore MD, US

International Classification:

C12Q 1/68
A61K 31/706

Abstract:

The invention provides methods for detecting a cellular proliferative disorder (e.g., urothelial cancer) in a subject by assessing the methylation status of the GULP1 promoter in a nucleic acid sample. The methods of the invention are useful for diagnostic, prognostic as well as therapeutic regimen predictions.