The present invention concerns long-half derivative of the obesity protein OB. The invention specifically concerns OB protein-immunoglobulin chimeras and polyethylene glycol (PEG)-OB derivatives, which have extended half-life as compared to the corresponding native OB proteins. The invention further relates to methods for appetite and/or weight reducion and for treating other physiological conditions by using the long half-life derivatives of OB.
Frederic DeSauvage - Foster City CA Nancy Levin - Newbury Park CA Richard Vandlen - Hillsborough CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 39395
US Classification:
4241781, 4241791, 514 2, 530350
Abstract:
The present invention concerns long-half derivative of the obesity protein OB. The invention specifically concerns OB protein-immunoglobulin chimeras and polyethylene glycol (PEG)-OB derivatives, which have extended half-life as compared to the corresponding native OB proteins. The invention further relates to methods for treating obesity by using the long half-life derivatives of OB.
Evans, Latham and Campisi, A Professional Corporation One Post Street Suite 600, San Francisco, CA 94104 (415)4210288 (Office)
Licenses:
California - Active 1973
Education:
University of California, Hastings College of the Law Degree - JD - Juris Doctor - Law Graduated - 1973 University of California - Berkeley Degree - BA - Bachelor of Arts Graduated - 1969
Evans, Latham and Campisi A Professional Corporation One Post Street, Suite 600, San Francisco, CA 94104
Phone:
(415)4210288 (Phone)
Memberships:
Bar Association of San Francisco (Co-chair, Probate and Trust Litigation Subcommittee, 2000- 2008) State Bar of California (Member, Legal Service Section) California Women Lawyers Association San Francisco Probate Department Mediation Panel.
ISLN:
905491095
Admitted:
1973, California
University:
University of California at Berkeley, B.A., 1969
Law School:
Hastings College of the Law, University of California, J.D., 1973
Reported:
Alliance Mortgage Co. v. Rothwell, 10 Cal. 4th 1226 (1995); Bonnette vs. California Health & Welfare Agency, 525 F. Supp. 128 (N.D. Ca. 1981).
Links:
Site
Biography:
Solano County Legal Assistance, 1974-1981, 1987-1988 and Directing Attorney, 1976-1981. Author: "Alliance and the Full Credit Bid Rule: Clarity or More Confusion?" CEB Real Property Law Reporter, Vol....
Rita Kilcoyne, Ann Kelly, Margo Stults, Jay Arbetman, Howard Mack, Kathy Klotz, Julie Henke, Bill Abell, Connie Tallman, Virginia Leider, Steve Kammann
Biography:
After GBN I went to NIU then transferred to UofA in Tucson. It was there that I ran ...