Pablo G Garcia

US Patent:

6991727, Jan 31, 2006

Filed:

Feb 16, 2005

Appl. No.:

11/059064

Inventors:

David C. Bomberger - Belmont CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 11/04
A61M 37/00

US Classification:

21032178, 21032179, 210634, 210645, 210649, 210790, 604 503, 422256

Abstract:

This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.

US Patent:

6995024, Feb 7, 2006

Filed:

Aug 27, 2001

Appl. No.:

09/940264

Inventors:

Chris D. Smith - Mountain View CA, US
Pablo E. Garcia - Redwood City CA, US
Thomas P. Low - Belmont CA, US
Eric J. Shrader - Belmont CA, US

Assignee:

SRI International - Menlo Park CA

International Classification:

G01N 1/10
B01L 3/02
B67D 5/22
B67D 5/08

US Classification:

436180, 422100, 222 57, 222639

Abstract:

An apparatus and device for dispensing femtoliter to nanoliter volumes of liquid samples are disclosed. The apparatus includes a liquid-support plate, two electrodes, a substrate, and a control unit. The liquid support plate has a plurality of liquid-support regions, each capable of supporting a liquid meniscus thereon. The first electrode contains a plurality of electrode connections, each operatively connected to one of the liquid support regions, for electrical contact with a meniscus supported in such region. The substrate has a first side confronting the plate and an opposite side, and a plurality of sample-holding regions formed in the first side. The second electrode is disposed adjacent one of the two substrate sides. Thus, a selected volume of the liquid can be ejected from or to one or more of the liquid-support regions to or from one or more of the sample-holding regions.

US Patent:

7033500, Apr 25, 2006

Filed:

Jun 21, 2002

Appl. No.:

10/178900

Inventors:

David C. Bomberger - Belmont CA, US
Bryan Chavez - San Jose CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US
Jeffrey J. Shimon - Mountain View CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 63/00
C02F 1/44

US Classification:

21032179, 210252, 210253, 210255, 2102572, 210263, 210645, 210649, 2103218, 210650, 210804, 210805, 210806, 210807, 604 503

Abstract:

This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.

US Patent:

7166223, Jan 23, 2007

Filed:

Sep 8, 2005

Appl. No.:

11/221617

Inventors:

David C. Bomberger - Belmont CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 11/00
B01D 11/04
B01D 63/02
B01D 69/08

US Classification:

210634, 21032178, 21032179, 2103218, 210645, 210649, 2102572, 422256, 604 503

Abstract:

This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.

US Patent:

7195710, Mar 27, 2007

Filed:

May 28, 2004

Appl. No.:

10/856046

Inventors:

David C. Bomberger - Belmont CA, US
Bryan Chavez - San Jose CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US
Jeffrey J. Shimon - Mountain View CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 63/02
B01D 36/00
B01D 11/04
B01D 11/00

US Classification:

2102572, 210252, 210253, 210255, 210263, 21032179, 2103218, 210645, 210650, 210660, 210804, 210805, 210806, 210807, 604 503

Abstract:

This invention is directed to systems and methods for removing lipids from a fluid or from lipid-containing organisms from a fluid, such as plasma. These systems combine a fluid with at least one extraction solvent, which causes the lipids to separate from the fluid or from the lipid-containing organisms. The separated lipids are removed from the fluid. The at least one extraction solvent is removed from the fluid or at least reduced to a concentration enabling the fluid to be administered to a patient without undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid or to a different patient for therapy.

US Patent:

7259553, Aug 21, 2007

Filed:

Apr 13, 2005

Appl. No.:

11/104740

Inventors:

Pablo Garcia - Menlo Park CA, US

Assignee:

SRI International - Menlo Park CA

International Classification:

G01B 7/30

US Classification:

32420725, 324213

Abstract:

A position-sensing system magnetically senses the position of a piston rod moving with respect to a cylinder. A magnetically hard layer on the piston rod provides a recording medium. Information is magnetically recorded in regions of the magnetically hard layer. These regions provide a relative encoding scheme for determining the position of the piston rod. Magnetic-field sensors are positioned over redundant tracks of magnetically recorded regions. Each magnetic-field sensor positioned over a given track senses the same magnetized regions while the piston rod moves with respect to the cylinder. Other magnetic-field sensors can sense ambient fields for use in performing common-mode rejection. A write head can dynamically repair damaged or erased regions detected by the magnetic-field sensors. Energized by a battery-backup power source, the magnetic-field sensors and associated circuitry can continue to track movement of the piston rod when the machinery is off.

US Patent:

7297261, Nov 20, 2007

Filed:

Jan 31, 2007

Appl. No.:

11/700626

Inventors:

David C. Bomberger - Belmont CA, US
Bryan Chavez - San Jose CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US
Jeffrey J. Shimon - Mountain View CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 63/02
B01D 36/00
B01D 11/04
B01D 11/00

US Classification:

210252, 210253, 210255, 210257, 210263, 21032179, 2103218, 210645, 210649, 210660, 210805, 210806, 604 503

Abstract:

Systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. A fluid is combined with at least one extraction solvent, which causes the lipids to separate from the fluid or from lipid-containing organisms. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to an acceptable concentration enabling the delipidated fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or stored for later use.

US Patent:

7297262, Nov 20, 2007

Filed:

Oct 30, 2006

Appl. No.:

11/589376

Inventors:

David C. Bomberger - Belmont CA, US
Pablo E. Garcia - Redwood City CA, US
Eric Hegwer - Menlo Park CA, US
Thomas P. Low - Belmont CA, US
Ripudaman Malhotra - San Carlos CA, US

Assignee:

Lipid Sciences, Inc. - Pleasanton CA

International Classification:

B01D 11/04
A61M 37/00
B01D 63/00

US Classification:

2102572, 210252, 210253, 210255, 210263, 21032179, 2103218, 21032178, 210645, 604 503

Abstract:

This invention is directed to systems and methods for removing lipids from a fluid, such as plasma, or from lipid-containing organisms. These systems contact a fluid with an extraction solvent, which causes the lipids in the fluid to separate from the fluid or causes lipids in the lipid-containing organisms to separate from the lipid-containing organism, using at least one hollow fiber contactor. The separated lipids are removed from the fluid. The extraction solvent is removed from the fluid or at least reduced to a level below a particular threshold enabling the fluid to be administered to a patient without the patient experiencing undesirable consequences. Once the fluid has been processed, the fluid may be administered to a patient who donated the fluid, to a different patient, or be stored.