Paul C Dempsey

US Patent:

8263387, Sep 11, 2012

Filed:

Jun 10, 2010

Appl. No.:

12/813285

Inventors:

Paul Pagano - Moorpark CA, US
Yanting Zhang - Santa Barbara CA, US
Jiangrong Karen Qian - Thousand Oaks CA, US
Hyongsok Tom Soh - Santa Barbara CA, US
Paul W. Dempsey - Studio City CA, US

Assignee:

Cynvenio Biosystems, Inc. - Westlake CA

International Classification:

C12M 1/00
G01N 15/06

US Classification:

4352831, 435 61, 4352882, 4352885, 422 681, 422527

Abstract:

The invention relates generally to fluid processing and, in particular aspects, processing fluids for detection, selection, trapping and/or sorting of particulate moieties. Sheath flow devices described allow isolation of target species from fluid samples while avoiding non-specific binding of unwanted species to the surfaces of the separation device. Biological fluid processing, detection, sorting or selection of cells, proteins, and nucleic acids is described. The invention finds particular use in diagnostic settings, analyzing a patient's medical condition, monitoring and/or adjusting a therapeutic regimen and producing cell based products.

US Patent:

20110165122, Jul 7, 2011

Filed:

Nov 10, 2010

Appl. No.:

12/943757

Inventors:

Arash Shahangian - Los Angeles CA, US
Genhong Cheng - Calabassas CA, US
Lucy S. Cheng - Calabassas CA, US
Kham Moc Trinh - Alhambra CA, US
Paul W. Dempsey - Studio City CA, US
Beichu Guo - Arcadia CA, US
Sherie L. Morrison - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 38/21
A61K 39/395
A61P 31/12
A61P 37/02
A61P 11/06
A61P 3/10
A61P 37/08
A61P 19/02

US Classification:

424 856, 4241341, 424 857, 424 854

Abstract:

Compounds compositions and methods of modulating the immune response are provided. The method uses fusion proteins of a cytokine and an antibody to potentiate the action of the cytokine.

US Patent:

20120301883, Nov 29, 2012

Filed:

Aug 3, 2012

Appl. No.:

13/566930

Inventors:

Paul Pagano - Moorpark CA, US
Yanting Zhang - Santa Barbara CA, US
Jiangrong Karen Qian - Thousand Oaks CA, US
Hyongsok Tom Soh - Santa Barbara CA, US
Paul W. Dempsey - Studio City CA, US

Assignee:

CYNVENIO BIOSYSTEMS, INC. - Westlake Village CA

International Classification:

C12N 13/00
C25B 7/00
C12Q 1/68
C12N 5/071
C12Q 1/02
C12Q 1/06

US Classification:

435 611, 4351739, 435 29, 435 39, 435325, 435 61, 435377, 204450

Abstract:

The invention relates generally to fluid processing and, in particular aspects, processing fluids for detection, selection, trapping and/or sorting of particulate moieties. Sheath flow devices described allow isolation of target species from fluid samples while avoiding non-specific binding of unwanted species to the surfaces of the separation device. Biological fluid processing, detection, sorting or selection of cells, proteins, and nucleic acids is described. The invention finds particular use in diagnostic settings, analyzing a patient's medical condition, monitoring and/or adjusting a therapeutic regimen and producing cell based products.