Hui Zheng - Edison NJ Ping Jiang - Trenton NJ Su Qian - Sayreville NJ Leonardus H. T. Van Der Ploeg - Scotch Plains NJ Philip Chun-Ying Wong - Timonium MD Sangram S. Sisodia - Chicago IL
Assignee:
Merck Co., Inc. - Rahway NJ Johns Hopkins University - Baltimore NJ
International Classification:
A01K 6700
US Classification:
800 12, 3 18, 3 22, 3 25, 435 29, 435354
Abstract:
The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and a transgenic non-human animal having only a non-native presenilin 1. The transgenic animals and cells derived therefrom can be used in the study of the expression pattern, activity and modulators of presenilin 1, in the study of the role of presenilin 1 in Alzheimers Disease and in the study of disorders of the central nervous system.
Rubber Composition, Process Of Preparing Same And Articles Made Therefrom
Ping Jiang - New City NY, US Chris Hartshorn - Ossining NY, US Eric R. Pohl - Mt. Kisco NY, US
Assignee:
Momentive Performance Materials Inc. - Albany NY
International Classification:
C08K 5/24
US Classification:
524263, 524430, 524431, 524432, 524433, 524437
Abstract:
There is provided herein a rubber composition comprising (a) at least one rubber component; (b) at least one silane-reactive filler; (c) optionally, at least one activating agent and, (d) at least one silane of the general Formula (1):[XXXSi—](G)[—Y—(CR-Z)] (1)wherein Xis selected hydrolyzable groups; Xand Xare independently hydrocarbons or selected hydrolyzable groups;.
Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same And Articles Manufactured Therefrom
Ping Jiang - New City NY, US Juan Alfonso - Hopewell Junction NY, US Eric R. Pohl - Mount Kisco NY, US
Assignee:
Momentive Performance Materials Inc. - Albany NY
International Classification:
C08K 5/54
US Classification:
524263, 524261
Abstract:
The invention is directed to an activated halo-containing aralkylsilanes possessing at least one hydrolyzable group bonded to a silicon atom and at least one halo functional group bonded to a carbon atom to which both the silicon atom and an aromatic group are covalently bonded. The invention is also directed to a process for making such a silane as well as its use in rubber compositions and articles containing such rubber compositions, such as tires.
Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same And Articles Manufactured Therefrom
Renjie Zhou - Plainsboro NJ, US Emanuel Cooper - Scarsdale NY, US Michael B. Korzenski - Danbury CT, US Ping Jiang - Danbury CT, US
Assignee:
ADVANCED TECHNOLOGY MATERIALS, INC. - Danbury CT
International Classification:
G03F 7/42
US Classification:
510176
Abstract:
A method and mineral acid-containing compositions for removing bulk and/or hardened photoresist material from microelectronic devices have been developed. The mineral acid-containing composition includes at least one mineral acid, at least one sulfur-containing oxidizing agent, and optionally at least one metal ion-containing catalyst. The mineral acid-containing compositions effectively remove the hardened photoresist material while not damaging the underlying silicon-containing layer(s).
Modified Hyaluronidases And Uses In Treating Hyaluronan-Associated Diseases And Conditions
- San Diego CA, US Ping Jiang - Wilmington DE, US Curtis B. Thompson - San Diego CA, US
International Classification:
A61K 38/47 A61K 31/337 C12N 9/26 C12N 11/08
Abstract:
Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and disorders. In one example, the products include an additional agent or treatment. Such products can be used in methods for administering the products to treat the hyaluronan-associated diseases and conditions, for example, hyaluronan-associated cancers, for example, hyaluronan-rich tumors. The methods include administration of the hyaluronan degrading enzyme composition alone or in combination with other treatments. Also provided are methods and compositions for providing sustained treatment effects in hyaluronan-associated diseases and conditions.