Hui Zheng - Edison NJ Ping Jiang - Trenton NJ Su Qian - Sayreville NJ Leonardus H. T. Van Der Ploeg - Scotch Plains NJ Philip Chun-Ying Wong - Timonium MD Sangram S. Sisodia - Chicago IL
Assignee:
Merck Co., Inc. - Rahway NJ Johns Hopkins University - Baltimore NJ
International Classification:
A01K 6700
US Classification:
800 12, 3 18, 3 22, 3 25, 435 29, 435354
Abstract:
The present invention relates to a transgenic non-human animal embryo lacking native presenilin 1 and a transgenic non-human animal having only a non-native presenilin 1. The transgenic animals and cells derived therefrom can be used in the study of the expression pattern, activity and modulators of presenilin 1, in the study of the role of presenilin 1 in Alzheimers Disease and in the study of disorders of the central nervous system.
Rubber Composition, Process Of Preparing Same And Articles Made Therefrom
Ping Jiang - New City NY, US Chris Hartshorn - Ossining NY, US Eric R. Pohl - Mt. Kisco NY, US
Assignee:
Momentive Performance Materials Inc. - Albany NY
International Classification:
C08K 5/24
US Classification:
524263, 524430, 524431, 524432, 524433, 524437
Abstract:
There is provided herein a rubber composition comprising (a) at least one rubber component; (b) at least one silane-reactive filler; (c) optionally, at least one activating agent and, (d) at least one silane of the general Formula (1):[XXXSi—](G)[—Y—(CR-Z)] (1)wherein Xis selected hydrolyzable groups; Xand Xare independently hydrocarbons or selected hydrolyzable groups;.
Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same And Articles Manufactured Therefrom
Ping Jiang - New City NY, US Juan Alfonso - Hopewell Junction NY, US Eric R. Pohl - Mount Kisco NY, US
Assignee:
Momentive Performance Materials Inc. - Albany NY
International Classification:
C08K 5/54
US Classification:
524263, 524261
Abstract:
The invention is directed to an activated halo-containing aralkylsilanes possessing at least one hydrolyzable group bonded to a silicon atom and at least one halo functional group bonded to a carbon atom to which both the silicon atom and an aromatic group are covalently bonded. The invention is also directed to a process for making such a silane as well as its use in rubber compositions and articles containing such rubber compositions, such as tires.
Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same And Articles Manufactured Therefrom
Compositions are provided which comprises an active hydrogen-containing resin, a flexibilizer and at least one curing agent. The cured compositions possess enhanced flexibility while maintaining hardness, and are highly suitable for applications such as coatings, adhesives, sealants, gaskets, industrial rubber goods, and the like.
(Meth)Acryloxy-Containing Trisiloxane, Siloxane-Containing Polymers And Biomedical Devices Therefrom
- Waterford NY, US Ping Jiang - New City NY, US Vikram Kumar - Tarrytown NY, US Anubhav Saxena - Bangalore, IN Umapathy Senthhikumar - Bangalore, IN Eric Pohl - Mount Kisco NY, US Kendall Guyer - Bartlett IL, US
International Classification:
C08F 230/08 G02B 1/04 C09D 143/04 C07F 7/08
Abstract:
There is provided a trisiloxane having a 3-(meth)acryloxy-substituted (hydroxylcyclohexyl)ethyl group, useful in making water absorbing silicone-hydrogel films for biomedical devices, such as contact lens, and a process for producing these monomers. This invention also provides for copolymers made from the trisiloxane having a 3-(meth)acryloxy-substituted (hydroxylcyclohexyl)ethyl group described herein.