Rebecca R Roberts

US Patent:

20040091462, May 13, 2004

Filed:

Aug 20, 2003

Appl. No.:

10/645744

Inventors:

Steve Lin - Gainesville FL, US
Luis Avila - Arlington MA, US
Arthur Coury - Boston MA, US
Hidegard Kramer - Westport CT, US
Laurence Roth - Windham NH, US
Rebecca Roberts - High Springs FL, US
Michael Sly - Gainesville FL, US

International Classification:

A61K045/00
A61K009/14

US Classification:

424/093700, 424/486000

Abstract:

Various embodiments of the present invention relate to compositions for delivering bone growth inducing material (e.g., to viable bone and/or other skeletal tissues to repair defects and the like). More particularly, various embodiments of the present invention relate to delivery mechanisms for an osteotherapeutic material (e.g., osteoinductive and/or osteoconductive materials), including (but not limited to) demineralized bone matrix (“DBM”) and cortical-cancellous bone chips (“CCC”). Certain compositions according to various embodiments of the present invention may comprise mixtures of a physiologically acceptable biodegradable carrier, an osteoinductive material, and/or an osteoconductive material (e.g., DBM and CCC). The compositions may thus be applied (for example, to defective bone tissue and/or other viable tissue) to induce formation of new bone. Other embodiments of the present invention relate to the preparation of compositions and methods of using such compositions.