A self-contained housing for the drive chain of a conventional chain-driven motorcycle comprising a front section, enclosing the motorcycle drive sprocket and a portion of the drive chain, and a rear section, enclosing the rear wheel sprocket and the remaining portion of the chain, both sections being joined together by a flexible coupling to form a single, integrated unit. Sealing interfaces are provided where the housing mates with the motorcycle transmission case and the rear wheel hub to prevent contaminants from entering the housing and also to prevent leakage of a pool of lubricating oil that is maintained within the housing to continuously lubricate the drive chain and sprocket. The forward end of the housing is reinforced to prevent the chain from flying loose and causing injury to the motorcycle operator or damage to the engine casing should the chain break while it is in motion.