Robert Allen Hinz

US Patent:

6714815, Mar 30, 2004

Filed:

Jan 13, 2003

Appl. No.:

10/341120

Inventors:

Richard Guy - San Francisco CA
Girish Rao - Rutherford NJ
Christopher Cullander - Berkeley CA
Robert S. Hinz - San Francisco CA
Peretz Glikfeld - Ness-Ziona, IL

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61N 130

US Classification:

604 20, 600345, 600347

Abstract:

The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises: (a) a positive electrode; (b) a negative electrode, and (c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample. The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal. The present invention also relates to the use of iontophoresis to determine the level of a charged molecule in a living mammal, and with the use of a feedback mechanism, administer appropriate levels of therapeutic substances.

US Patent:

57307148, Mar 24, 1998

Filed:

Sep 26, 1994

Appl. No.:

8/312400

Inventors:

Richard Guy - San Francisco CA
Girish Rao - San Francisco CA
Peretz Glikfeld - Ness-Ziona, IL
Christopher Cullander - Berkeley CA
Robert S. Hinz - Mill Valley CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61N 130

US Classification:

604 20

Abstract:

The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises: (a) a positive electrode; (b) a negative electrode, and (c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample. The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal. The present invention also relates to the use of iontophoresis to determine the level of a charged molecule in a living mammal, and with the use of a feedback mechanism, administer appropriate levels of therapeutic substances.

US Patent:

52795438, Jan 18, 1994

Filed:

Apr 30, 1992

Appl. No.:

7/879060

Inventors:

Peretz Glikfeld - San Francisco CA
Christopher Cullander - Berkeley CA
Robert S. Hinz - Mill Valley CA
Richard H. Guy - Daley City CA

Assignee:

The Regents of The University of California - Oakland CA

International Classification:

A61N 130

US Classification:

604 20

Abstract:

The present invention relates to an vitro device for the removal of ionized substances from a membrane sample without mechanical penetration, which device comprises: (a) a positive electrode; (b) a negative electrode, and (c) electrical insulation between subpart (a) and (b), wherein the positive electrode, and the negative electrode, and electrical insulation are positioned on the same side of the membrane sample. The present invention also relates to a device for the removal of or delivery of ionized substances to a mammal through intact skin or mucosal membrane without mechanical penetration, which device comprises: (a) a positive electrode, (b) a negative electrode, and (c) an electrically insulating material between subpart (a) and (b), wherein the positive electrode, negative electrode and insulating material are physically positioned so that each present a common surface of the device for contact with the same surface of the skin or mucosal membrane of the mammal. The present invention also relates to the use of iontophoresis to determine the level of a charged molecule in a living mammal, and with the use of a feedback mechanism, administer appropriate levels of therapeutic substances.