Samuel J Lin

US Patent:

20110251652, Oct 13, 2011

Filed:

Apr 8, 2011

Appl. No.:

13/083014

Inventors:

Jongyoon Han - Bedford MA, US
Amr Rabie - Cairo, EG
Rahul Sarpeshkar - Arlington MA, US
Samuel J. Lin - Needham MA, US

Assignee:

BETH ISRAEL DEACONESS MEDICAL CENTER, INC. - Boston MA
MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA

International Classification:

A61N 1/36
C12N 13/00

US Classification:

607 2, 4351731

Abstract:

A neural prosthetic device is provided that includes one or more ion-selective membranes enabling electrically-controlled local modulation of ion concentrations around a nerve so as to achieve different excitability states of the nerve for electrical stimulation or inhibition of nerve signal propagation.

US Patent:

20130030510, Jan 31, 2013

Filed:

Oct 5, 2012

Appl. No.:

13/645986

Inventors:

MASSACHUSETTS INSTITUTE OF TECHNOLOG - Cambridge MA, US
Samuel J. Lin - Needham MA, US
Rohat Melik - Cambridge MA, US
Amr Rabie - Cairo, EG
Rahul Sarpeshkar - Arlington MA, US

Assignee:

BETH ISRAEL DEACONESS MEDICAL CENTER INC. - Boston MA
MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA

International Classification:

A61N 1/05

US Classification:

607118

Abstract:

A neural prosthetic device is provided that includes one or more ion-selective membranes enabled by electrically-controlled local modulation of ion concentrations around a nerve so as to achieve different excitability states of the nerve for electrical stimulation or inhibition of nerve signal propagation. The local modulation is achieved by positioning the nerve in a bipolar perpendicular arrangement so as to modulate the ion concentrations of the one or more ion-selective membranes in situ to change the nerve excitability locally at the site of electrical stimulation or along the nerve for on-demand suppression of nerve propagation.

US Patent:

20160095599, Apr 7, 2016

Filed:

Apr 24, 2014

Appl. No.:

14/785047

Inventors:

- Medford MA, US
- Boston MA, US
David L. Kaplan - Concord MA, US
Ahmed Ibrahim - Brookline MA, US
Samuel Lin - Dover MA, US
Abdurrahman Abdurrob - Winchester MA, US

Assignee:

Trustees of Tufts College - Medford MA
Beth Israel Deaconess Medical Center, Inc. - Boston MA

International Classification:

A61B 17/11

Abstract:

A bioresorbable drug-eluting biopolymer suture-free blood vessel anastomosis devices can be deployed to join two blood vessels and resorbed by the body over a predetermined time period after the blood vessel has become joined. The anastomosis device can include a hollow tube that is inserted interconnect the two vessels to be jointed. A non-piercing suture is wrapped around the vessel to secure the anastomosis. The anastomosis device can include hollow tube that extends along an axis from a first end to a second end. The ends can be fitted with elements that facilitate mechanical attachment of the vessel to the anastomosis device and provide for a secure seal.