Seung K Choi

US Patent:

20180206024, Jul 19, 2018

Filed:

Jan 18, 2018

Appl. No.:

15/874112

Inventors:

- Irvine CA, US
Seung Jin Choi - Irvine CA, US

Assignee:

TCT MOBILE INC. - Irvine CA

International Classification:

H04R 1/10
H01L 35/02
H04R 1/02
H04R 5/04

Abstract:

A heat energy powered earphone is provided, which utilizes a thermoelectric (TE) module that is connected to an external heat exchanger clip. The clip can be affixed to a cool location such as the top of an ear, a hat, or other piece of clothing. The clip may connect to the TE module via a simple heat pipe. By using the clip, the earphone housing may be manufactured with a compact form factor that enables close insertion to the inner ear. Additionally, by providing an open hole in the TE module, audio waves can pass through unobstructed. Power management, wireless transmission, and audio playback circuitry may be provided via a tethered wire to an external electronics module. Interfacing methods are also provided, including a method for automatic pairing with an audio source upon insertion of the earphone, and a method for adjusting a fit of the earphone using audio feedback.

US Patent:

20170157212, Jun 8, 2017

Filed:

Dec 2, 2016

Appl. No.:

15/368341

Inventors:

- La Jolla CA, US
Seung Hyuk Choi - La Jolla CA, US

Assignee:

Salk Institute for Biological Studies - La Jolla CA

International Classification:

A61K 38/17
A61K 45/06
C07K 14/47

Abstract:

Disclosed is a polypeptide that includes amino acids 183-222 of CRIF, wherein the polypeptide does not include the full length CRIF1 amino acid sequence. Also disclosed is a nucleic acid molecule encoding this polypeptide, vectors including this nucleic acid molecule, and host cells transformed with these vectors. In some embodiments, methods are disclosed for treating a subject with cancer, comprising administering to the subject a therapeutically effective amount of an inhibitor of CDK12/CRIF1 interaction, thereby treating the cancer in the subject. In specific non-limiting examples, these methods can utilize CRIF1 polypeptides, nucleic acids encoding these polypeptides, and vectors including these nucleic acids.