Steven J Pedersen

US Patent:

20100331309, Dec 30, 2010

Filed:

Jun 28, 2010

Appl. No.:

12/824355

Inventors:

Xinchao Chen - Schenectady NY, US
Scott Alan Frank - Indianapolis IN, US
David Michael Remick - Fishers IN, US
Steven Wayne Pedersen - Indianapolis IN, US

Assignee:

ELI LILLY AND COMPANY - Indianapolis IN

International Classification:

A61K 31/55
C07D 403/12
A61P 9/10

US Classification:

51421301, 540593

Abstract:

Compounds of a formulaentitled, trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin--yl]methyl]-cyclohexanecarboxylic acid, as a free acid or a pharmaceutically acceptable salt thereof; and hydrates and other solvates in crystalline form; pharmaceutical formulations; and methods of use are disclosed.

US Patent:

20120058990, Mar 8, 2012

Filed:

Jun 28, 2010

Appl. No.:

13/318874

Inventors:

Xinchao Chen - Schenectady NY, US
Scott Alan Frank - Indianapolis IN, US
Steven Wayne Pedersen - Indianapolis IN, US
David Michael Remick - Fishers IN, US

Assignee:

ELI LILLY AND COMPANY - Indianapolis IN

International Classification:

A61K 31/55
A61P 9/10
C07D 403/12

US Classification:

51421301, 540593

Abstract:

Abstract Compounds of a formula entitled, trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid, as a free acid or a pharmaceutically acceptable salt thereof, hydrate, and hydrate in crystalline form; pharmaceutical formulations; and methods of use are disclosed.