Susan I Golden

US Patent:

20120184004, Jul 19, 2012

Filed:

Jul 22, 2010

Appl. No.:

13/383409

Inventors:

Steve A. Kay - San Diego CA, US
Ewa Lis - Lakeside CA, US
Susan Golden - Del Mar CA, US
Michael Melnick - San Francisco CA, US
Dawn M. Adin - Germantown MD, US
James W. Golden - Del Mar CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

C12P 7/64
C12N 1/13
C12N 1/00
C12N 15/63

US Classification:

435134, 4353201, 4352572, 4353171

Abstract:

Provided herein are methods and compositions for the production of renewable fatty acids from photosynthetic prokaryotic microorganisms, such as a blue green algae, any specie of the phylum Cyanophyta, a chloroplast of a green algae and/or a Cyanobacterium. Engineered or natural strains of these organisms or organelles can be used to produce both saturated and unsaturated fatty acids with variable chain length specificity from 8-18 carbons. The fatty acids can then be secreted into the culture medium, allowing for rapid, continuous and efficient separation of fatty acid product without harvesting of cell mass.