Bristol-Myers Squibb since Mar 2012
Research Investigator I
Bristol-Myers Squibb 2006 - 2012
Research Scientist I, II
Johnson & Johnson Aug 2005 - Mar 2006
Associate Research Scientist
The Childrens Hospital of Philadelphia Jan 2001 - Jul 2005
Research Assistant, Neonatology
Education:
University of the Sciences in Philadelphia
Ph.D., Pharmacology 2012
University of the Sciences in Philadelphia
M.S., Pharmacology/Toxicology
Philadelphia College of Pharmacy and Science
B.S., Pharmacology/Toxicology
Skills:
Oncology Drug Discovery In Vivo Drug Development Pharmacology Assay Development Epigenetics Biomarker Discovery
2012 to 2000 Research Investigator, Oncology Biology, Bristol-Myers SquibbPost-Doctorate Work
2012 to 2000 Research Investigator, OncologyPost-Doctorate Work
2009 to 2012 Research Scientist II, OncologyPost-Doctorate Work
2006 to 2009 Research Scientist I, OncologyJanssen Pharmaceuticals
2005 to 2006 Associate Research Scientist, OncologyChildren's Hospital of Philadelphia Philadelphia, PA 2000 to 2005 Research Assistant
Education:
University of the Sciences in Philadelphia Philadelphia, PA 2012 Ph.D. in PharmacologyUniversity of the Sciences in Philadelphia Philadelphia, PA M.S. in PharmacologyPhiladelphia College of Pharmacy and Science B.S. in Pharmacology and Toxicology
- Horsham PA, US Donna KLEIN - Philadelphia PA, US Neeraj KOHLI - North Wales PA, US Theresa Marie MCDEVITT - Warminster PA, US Steven J. ORCUTT - Eagleville PA, US
International Classification:
C07K 16/30 A61P 35/04 A61K 47/68
Abstract:
Disclosed herein are antibodies or antigen binding fragments thereof that bind prostate specific membrane antigen (PSMA), polynucleotides, vectors, host cells, radioconjugates, antibody drug conjugates and methods of treating cancer using the same.
Proteins Comprising Kallikrein Related Peptidase 2 Antigen Binding Domains And Their Uses
- Horsham PA, US John Lee - North Wales PA, US Jinquan Luo - Malvern PA, US Theresa McDevitt - Warminster PA, US Fei Shen - Collegeville PA, US Degang Song - Wynnewood PA, US Raymond Brittingham - Spring House PA, US Sathyadevi Venkataramani - Blue Bell PA, US Sanjaya Singh - Blue Bell PA, US Yonghong Zhao - Eagleville PA, US Fang Yi - Collegeville PA, US Sherry Lynn La Porte - Horsham PA, US
International Classification:
C07K 16/28 C07K 16/34
Abstract:
Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
- Horsham PA, US Shalom Goldberg - Merion Station PA, US Joseph Erhardt - Sellersville PA, US Rhys Salter - Doylestown PA, US Theresa McDevitt - Warminster PA, US
International Classification:
C07B 59/00 C07K 16/30 A61K 51/10 A61P 35/00
Abstract:
Improved methods of radiolabeling antibodies using click chemistry are described. Also described are pharmaceutical compositions and uses related to the radiolabeled antibodies produced by the methods.
- Horsham PA, US Tammy Bush - Perkasie PA, US Rosa Maria Fernandes Cardoso - Berwyn PA, US Ellen Chi - Del Mar CA, US Judith Ann Connor - Vista CA, US Thai Quang Dinh - Solana Beach CA, US Derrick Lemon Domingo - Carlsbad CA, US John Michael Jones - Ambler PA, US Colleen Kane - Flourtown PA, US Bethany Kay Mattson - Conoshohocken PA, US Theresa Marie McDevitt - Warminster PA, US Jill Marie Mooney - San Diego CA, US Richard Stephen Tawadros - Norristown PA, US Hong Mimi Zhou - San Diego CA, US
International Classification:
C07K 16/30 C07K 16/28
Abstract:
The present invention relates to antibodies specifically binding PSMA or PSMA and CD3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.