Wei Li

US Patent:

8303946, Nov 6, 2012

Filed:

Sep 2, 2003

Appl. No.:

10/654273

Inventors:

Margo A. Brinton - Decatur GA, US
Wei Li - Wayland MA, US

Assignee:

Georgia State University Foundation, Inc. - Atlanta GA

International Classification:

C12N 15/00
C12N 15/33
C12N 15/86
C12Q 1/68
C12Q 1/70

US Classification:

424 931, 424 9321, 424 932, 435456, 435 5, 435 61

Abstract:

The present invention is directed to methods and compositions that are effective in the inhibition of viral replication. In particular, the methods and compositions are effective at interfering with the activity of host cell proteins required in viral replication. For example, an embodiment of the invention is directed to inhibition of flavivirus replication wherein the replication is effected by changing the normal interactions of the host cell protein TIAR or TIA-1.

US Patent:

20050228250, Oct 13, 2005

Filed:

Nov 21, 2002

Appl. No.:

10/496435

Inventors:

Ingmar Bitter - Rockville MD, US
Wei Li - East Brunswick NJ, US
Michael Meissner - Port Jefferson NY, US
Frank Dachille - Amityville NY, US
Soren Grimm - Wurmlingen, DE
George Economos - Bayport NY, US

International Classification:

A61B005/05

US Classification:

600407000

Abstract:

A user interface () comprises an image area that is divided into a plurality of views for viewing corresponding 2-dimensional and 3-dimensional images of an anatomical region. Tool control panes (-) can be simultaneously opened and accessible. The segmentation pane () enables automatic segmentation of components of a displayed image within a user-specified intensity range or based on a predetermined intensity

US Patent:

20070179855, Aug 2, 2007

Filed:

Jan 24, 2007

Appl. No.:

11/657047

Inventors:

Ismael Enrique Arciniegas Rueda - Arlington VA, US
Anil Kumar Suri - Tarrytown NY, US
Vikram Bakshi - Westport CT, US
Glenn Bradley Christensen - New Lenox IL, US
Andrew Mark Singer - Baltimore MD, US
Gary R. Bradley - Lemont IL, US
Brian Hayduk - Tarrytown NY, US
Abhinav Krishna - Chevy Chase MD, US
Alvaro Ignacio Arciniegas Rueda - Troy NY, US
Wei Li - Parsippany NJ, US

Assignee:

Constellation Energy Group, Inc. - Baltimore MD

International Classification:

G07G 1/14

US Classification:

705 14, 705412

Abstract:

A method of determining an optimal energy portfolio for a customer includes: quantifying the customer's risk/reward profile; obtaining customer data, including historical and forward customer data, said customer data including at least customer budgetary constraints; obtaining market data, including historical and forward market data; and determining, as the optimal energy portfolio for the customer, an energy portfolio based at least in part on (i) the customer's risk/reward profile, (ii) the customer's budget constraints, (iii) the customer data; and (iv) the market data.

US Patent:

20100166704, Jul 1, 2010

Filed:

Apr 7, 2008

Appl. No.:

12/082095

Inventors:

Margo A. Brinton - Decatur GA, US
Mohamed M. Emara - Roswell GA, US
Wei Li - Wayland MA, US

International Classification:

A61K 38/21
A61K 39/395
A61K 35/76
A61K 38/00
A61K 38/16
A61K 31/7088

US Classification:

424 854, 4241301, 424 936, 514 2, 514 12, 514 44 R

Abstract:

The present invention is directed to methods and compositions that are effective in the inhibition of viral replication. In particular, the methods and compositions are effective at interfering with the activity of host cell proteins required in viral replication. For example, an embodiment of the invention is directed to inhibition of flavivirus replication wherein the replication is affected by changing the normal interactions of the host cell protein TIAR or TIA-1.

US Patent:

20220202984, Jun 30, 2022

Filed:

Mar 15, 2022

Appl. No.:

17/695112

Inventors:

- Norcross GA, US
Wei Li - Norcross GA, US
Yuan Di - Norcross GA, US
Annie You - Norcross GA, US
Low Wee Fong - Singapore, SG

International Classification:

A61L 9/22
A61L 9/20
A61L 2/10
A61L 2/24
A61L 2/26

Abstract:

A germicidal device includes a purification/disinfection and LED lighting member configured to generate UVC light and negative air ions for destroying microorganisms and removing odors in a space in which the purification and sterilization member is placed; a sensing member configured to detect at least one event occurred in said space in real time; and a microcontroller unit coupled with the purification and sterilization member and the sensing member for controlling operations of the purification and sterilization member in a respective state in accordance with the at least one event occurred in said space and energy saving. The UVC light has one or more wavelengths in a range of about 100-400 nm.

US Patent:

20230095075, Mar 30, 2023

Filed:

Nov 22, 2022

Appl. No.:

18/058064

Inventors:

- Bethesda MD, US
Wei LI - Potomac MD, US
Kiyoharu Joshua MIYAGISHIMA - Laurel MD, US

International Classification:

A61K 31/4985
A61K 31/336
A61K 31/34
A61K 38/08

Abstract:

A composition for preserving viability of cells, tissues, or organs at a low temperature is provided. The composition includes a mitochondrial uncoupling agent, at least one protease inhibitor, and a reducing agent. Methods to protect cells, tissues, or organs from exposure to cold and other metabolic stress are also provided.

US Patent:

20210024482, Jan 28, 2021

Filed:

May 15, 2020

Appl. No.:

16/875479

Inventors:

- Cambridge MA, US
Harry Rogoff - Wrentham MA, US
Youzhi Li - Westwood MA, US
Jifeng Liu - Winchester MA, US
Wei Li - Wayland MA, US

Assignee:

Sumitomo Dainippon Pharma Oncology, Inc. - Cambridge MA

International Classification:

C07D 307/92
A61K 31/38
A61K 31/343
A61P 35/00
C07D 333/74

Abstract:

The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such corn pounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof and to the pharmaceutical compositions of relevant compounds, and to the specific methods of administration of these compounds.

US Patent:

20200368230, Nov 26, 2020

Filed:

Aug 20, 2018

Appl. No.:

16/636945

Inventors:

- Bethesda MD, US
Wei Li - Potomac MD, US
Kiyoharu Josh Miyagishima - Laurel MD, US

International Classification:

A61K 31/4985
A61K 31/336
A61K 38/08
A61K 31/34

Abstract:

A composition for preserving viability of cells, tissues, or organs at a low temperature is provided. The composition includes a mitochondrial uncoupling agent, at least one protease inhibitor, and a reducing agent. Methods to protect cells, tissues, or organs from exposure to cold and other metabolic stress are also provided.

Address:

523 Florida Ave APT 202, Herndon, VA 20170

VIN:

1HGCM56357A039723

Make:

HONDA

Model:

ACCORD

Year:

2007