Wei Li

US Patent:

7420001, Sep 2, 2008

Filed:

Dec 1, 2004

Appl. No.:

11/001589

Inventors:

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/343
C07D 307/81

US Classification:

514469, 514470, 549466, 549467

Abstract:

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

US Patent:

8184120, May 22, 2012

Filed:

Feb 17, 2009

Appl. No.:

12/371959

Inventors:

Wei Hong - Edison NJ, US
Wei Li - Princeton NJ, US

Assignee:

Siemens Aktiengesellschaft - München

International Classification:

G06T 17/00
G06T 15/00
G06T 15/04

US Classification:

345424, 345582

Abstract:

Described herein is a system and method for facilitating large volume data processing and rendering. An exemplary system includes at least one processor coupled to a first memory, wherein the processor is configured to organize the large volume data in the first memory into one or more bricks. In addition, at least one graphics processing unit (GPU) is coupled to the processor and a second memory. The GPU is configured to process at least one or more bricks transferred from the first memory to the second memory to produce intermediate processing results, and to further render the intermediate processing results.

US Patent:

8563543, Oct 22, 2013

Filed:

Oct 6, 2010

Appl. No.:

13/392955

Inventors:

Jack D. Scott - Scotch Plains NJ, US
Andrew W. Stamford - Chatham NJ, US
Eric J. Gilbert - Scotch Plains NJ, US
Jared N. Cumming - Garwood NJ, US
Ulrich Iserloh - Hoboken NJ, US
Lingyan Wang - East Brunswick NJ, US
Wei Li - Belle Mead NJ, US

Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ

International Classification:

A61K 31/54

US Classification:

5142225, 544 8

Abstract:

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R, R, R, R, R, R, ring A, ring B, ring C, m, n, p, q, -L-, -L-, L-, and L- is selected independently and as defined herein. The compounds of the invention have, surprisingly and advantageously, improved solution stability. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers Disease, are also disclosed.

US Patent:

20030151604, Aug 14, 2003

Filed:

Nov 21, 2002

Appl. No.:

10/301399

Inventors:

Arie Kaufman - Plainview NY, US
Wei Li - Stony Brook NY, US

Assignee:

RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

International Classification:

G06T015/00

US Classification:

345/419000

Abstract:

A system and method for texture-based volume rendering accelerated by contouring texture hulls is provided. Bounding geometries, such as rectangles, cuboids, or the like surrounding the non-empty regions as well as the contouring borders of the non-empty regions are found. The bounding shapes are treated as the hulls of the non-empty sub-textures. The nonempty sub-textures are stored and rendered. Texels outside the hulls are skipped.

US Patent:

20090029906, Jan 29, 2009

Filed:

May 1, 2006

Appl. No.:

11/913038

Inventors:

Rui Rong Yuan - Fort Lee NJ, US
Wei Ping Li - Kearny NJ, US
Joseph Menonna - Dumont NJ, US
Yasuhiro Maeda - Belle Mead NJ, US
Peter Dowling - Fort Lee NJ, US

Assignee:

UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY - Newark NJ

International Classification:

C07K 14/575
C07K 9/00
A61K 38/22
A61K 38/14
A61P 29/00
A61P 37/00

US Classification:

514 8, 530397, 530322

Abstract:

The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.

US Patent:

20100137298, Jun 3, 2010

Filed:

Jun 13, 2008

Appl. No.:

12/138752

Inventors:

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/5377
G01N 33/573
C12N 9/99
A61K 31/4439
A61K 31/425
A61K 31/428
A61K 31/381
A61K 31/343
C07D 413/12
C07D 405/10
C07D 277/02
C07D 275/02
C07D 209/42
C07D 333/52
C07D 307/78
A61P 35/00

US Classification:

5142315, 435 74, 435184, 514339, 514367, 514373, 514443, 514469, 544153, 5462841, 548200, 548214, 548492, 549 57, 549468

Abstract:

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

US Patent:

20220310072, Sep 29, 2022

Filed:

Jun 3, 2020

Appl. No.:

17/616129

Inventors:

- Mountain View CA, US
Ruoming Pang - New York NY, US
David Rybach - Mountain View CA, US
Yanzhang He - Palo Alto CA, US
Rohit Prabhavalkar - Mountain View CA, US
Wei Li - Fremont CA, US
Mirkó Visontai - Mountain View CA, US
Qiao Liang - Redwood City CA, US
Trevor Strohman - Sunnyvale CA, US
Yonghui Wu - Fremont CA, US
Ian C. McGraw - Menlo Park CA, US
Chung-Cheng Chiu - Sunnyvale CA, US

International Classification:

G10L 15/16
G10L 15/32
G10L 15/05

Abstract:

Two-pass automatic speech recognition (ASR) models can be used to perform streaming on-device ASR to generate a text representation of an utterance captured in audio data. Various implementations include a first-pass portion of the ASR model used to generate streaming candidate recognition(s) of an utterance captured in audio data. For example, the first-pass portion can include a recurrent neural network transformer (RNN-T) decoder. Various implementations include a second-pass portion of the ASR model used to revise the streaming candidate recognition(s) of the utterance and generate a text representation of the utterance. For example, the second-pass portion can include a listen attend spell (LAS) decoder. Various implementations include a shared encoder shared between the RNN-T decoder and the LAS decoder.

US Patent:

20200306176, Oct 1, 2020

Filed:

Mar 27, 2019

Appl. No.:

16/366404

Inventors:

- Edison NJ, US
Wei LI - Edison NJ, US
Zhihong ZHANG - Edison NJ, US

International Classification:

A61K 9/00
A61K 31/4422
A61K 47/10
A61K 47/38
A61K 47/32
A61K 31/55

Abstract:

Disclosed is an osmotic pump controlled release formulation, comprising a core and a membrane, wherein the membrane is coated on an outer surface of the core, the formulation has at least one channel, the core is communicated with to the outer surface of the formulation via the channel, lateral length of the channel is 1.40 mm-2.50 mm, and depth of the channel is 2.05 mm-2.95 mm.