Yan W Wu

US Patent:

7400627, Jul 15, 2008

Filed:

Nov 7, 2003

Appl. No.:

10/702456

Inventors:

Yan Wu - Morganville NJ, US
Song Bi - Piscataway NJ, US
Timothy Bornemisza - Middletown NJ, US

Assignee:

Brooktree Broadband Holding, Inc. - Newport Beach CA

International Classification:

H04L 12/28
H04J 3/24

US Classification:

370392, 3703951, 370474

Abstract:

Disclosed are exemplary techniques for compressing ATM cells by substituting reduced headers for the original headers. A header table may be maintained at the transmitting end whereby headers are stored in table entries based on a table index generated from a hash function applied to the headers. A copy of the header table may be maintained at the receiving end and may be updated by populating idle cells with header table contents. Upon receipt of a reduced ATM cell at the receiving end, the reduced header may be replaced with a full header obtained from the copy of the header table maintained at the receiving end. The present invention further provides techniques for registration and management of hash collisions.

US Patent:

7720071, May 18, 2010

Filed:

Mar 5, 2008

Appl. No.:

12/042930

Inventors:

Yan Wu - Morganville NJ, US
Song Bi - Piscataway NJ, US
Timothy Bornemisza - Middletown NJ, US

Assignee:

Ikanos Communications, Inc. - Fremont CA

International Classification:

H04L 12/28
H04J 3/24

US Classification:

370392, 3703951, 370474

Abstract:

Disclosed are exemplary techniques for compressing ATM cells by substituting reduced headers for the original headers. A header table may be maintained at the transmitting end whereby headers are stored in table entries based on a table index generated from a hash function applied to the headers. A copy of the header table may be maintained at the receiving end and may be updated by populating idle cells with header table contents. Upon receipt of a reduced ATM cell at the receiving end, the reduced header may be replaced with a full header obtained from the copy of the header table maintained at the receiving end. The present invention further provides techniques for registration and management of hash collisions.

US Patent:

7813434, Oct 12, 2010

Filed:

Nov 14, 2006

Appl. No.:

11/559772

Inventors:

Yan Wu - Morganville NJ, US
Lujing Cai - Morganville NJ, US
William Scholtz - Red Bank NJ, US
Ehud Langberg - Wayside NJ, US

Assignee:

Ikanos Communications, Inc. - Fremont CA

International Classification:

H04K 1/10
H04L 27/28

US Classification:

375260

Abstract:

Systems and methods for performing bit loading in a dual latency data transmission system. In a computer network, such as an XDSL-based network, carrier channels are allocated between two latency paths. Error sensitive information is transmitted over a latency path employing one or more forward error correction techniques. Latency sensitive information that is relatively more tolerant of errors is transmitted over the other latency path. Rather than employing the lowest coding gain for carrier channels having the two different latency paths, the highest coding gain for each path is used by applying different target S-N-R margins for carrier channels having different latency paths.

US Patent:

7972596, Jul 5, 2011

Filed:

Nov 18, 2005

Appl. No.:

11/719677

Inventors:

Yan Wu - Flemington NJ, US
Danny J. Hicklin - Montclair NJ, US
Peter Bohlen - New York NY, US

Assignee:

ImClone LLC - New York NY

International Classification:

A61K 39/395
C12P 21/08
C07K 16/18
C07K 16/28

US Classification:

4241301, 4241411, 4241431, 5303871, 53038815, 53038822

Abstract:

Monoclonal antibodies that are specific for vascular endothelial growth factor receptor 1 (VEGFR-I). This invention also provides nucleotide sequences encoding and amino acid sequences comprising variable heavy and light chain immunoglobulin molecules, including sequences corresponding to the complementarity determining regions of CDR1, CDR2, and CDR3. The invention also provides methods for generation and expression of anti -VEGFR-I antibodies and methods of treating angiogenic-related disorders and reducing tumor growth by administering anti-VEGFR-I antibodies.

US Patent:

8143025, Mar 27, 2012

Filed:

May 20, 2011

Appl. No.:

13/112152

Inventors:

Yan Wu - Flemington NJ, US
Peter Bohlen - New York NY, US
Daniel J. Hicklin - Upper Montclair NJ, US

Assignee:

ImClone LLC - New York NY

International Classification:

C12P 21/06
C12P 19/30
C07H 21/04

US Classification:

435 691, 4353201, 4352523, 435451, 435452, 536 2353

Abstract:

Monoclonal antibodies that are specific for vascular endothelial growth factor receptor 1 (VEGFR-I). This invention also provides nucleotide sequences encoding and amino acid sequences comprising variable heavy and light chain immunoglobulin molecules, including sequences corresponding to the complementarity determining regions of CDR1, CDR2, and CDR3. The invention also provides methods for generation and expression of anti-VEGFR-I antibodies and methods of treating angiogenic-related disorders and reducing tumor growth by administering anti-VEGFR-I antibodies.

US Patent:

8147834, Apr 3, 2012

Filed:

Oct 29, 2009

Appl. No.:

12/608034

Inventors:

Yan Wu - Flemington NJ, US

Assignee:

ImClone LLC - New York NY

International Classification:

A61K 39/395
C07K 16/18

US Classification:

4241331, 4241391, 5303879

Abstract:

The present invention is directed to antibodies against human transforming growth factor beta receptor II (TGFβRII), pharmaceutical compositions comprising antibodies and methods of using the antibodies, alone or in combination, for example, for treating cancer and fibrosis.

US Patent:

8418004, Apr 9, 2013

Filed:

Mar 14, 2011

Appl. No.:

13/046991

Inventors:

Massimo Sorbara - Freehold NJ, US
Patrick Duvaut - Tinton Falls NJ, US
Yan Wu - Morganville NJ, US

Assignee:

Ikanos Communications, Inc. - Fremont CA

International Classification:

G06F 11/00
G01R 31/28
H04B 1/38
H04B 3/46

US Classification:

714701, 714 48, 714 57, 714712, 714715, 375220, 375224, 37524027, 370242

Abstract:

Various embodiments are described for back channel communication. One embodiment is a method that comprises receiving data at customer premises equipment (CPE), determining at least one error in the received data, formatting the determined error for communication to a central office (CO), and sending the formatted error to the CO via a back channel, wherein the formatted error is sent between sync frames of a discrete multitone (DMT) superframe.

US Patent:

20040241160, Dec 2, 2004

Filed:

Jul 8, 2004

Appl. No.:

10/483919

Inventors:

Yan Wu - Flemington NJ, US
Shahin Rafii - Great Neck NY, US
Larry Witte - Stormville NY, US

International Classification:

A61K039/395
A61K031/00

US Classification:

424/143100, 514/001000

Abstract:

The present invention is directed to methods of inhibiting tumor cells by administering an antagonist which inhibits the VEGF/VEGFR-1 autocrine loop of tumor cells. Additional antagonists can be added to inhibit endothelial paracrine loop by inhibiting other VEGFRs expressed on endothelial cells, particularly VEGFR-2. Examples of antagonists include antibodies and small molecules. A preferred cancer for treatment is breast cancer.