Yan Wu

US Patent:

7803377, Sep 28, 2010

Filed:

Jun 6, 2007

Appl. No.:

11/759131

Inventors:

Minhong Yan - Foster City CA, US
Yan Wu - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

A61K 39/395
C07K 16/00
C12P 21/00
A61P 35/00
C07H 21/00
C12N 1/00
C12N 5/00
G01N 33/68

US Classification:

4241451, 436 86, 5303871

Abstract:

The invention provides anti-DLL4 antibodies, and compositions comprising and methods of using these antibodies.

US Patent:

7825221, Nov 2, 2010

Filed:

Aug 1, 2008

Appl. No.:

12/184969

Inventors:

Daniel K. Kirchhofer - Los Altos CA, US
Yan Wu - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C12P 21/08

US Classification:

5303873, 5303881, 5303917, 530350, 4241331

Abstract:

The invention provides methods and compositions for modulating hepatocyte growth factor activator function.

US Patent:

7834154, Nov 16, 2010

Filed:

Feb 8, 2008

Appl. No.:

12/028124

Inventors:

Alexander W. Koch - Millbrae CA, US
Scott Stawicki - San Francisco CA, US
Yan Wu - Foster City CA, US
Richard Carano - San Ramon CA, US
Ryan J. Watts - San Mateo CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 16/00
C07K 17/00
C07K 17/14
C12P 21/08
A61K 39/395
A61K 39/00

US Classification:

5303871, 5303873, 5303911, 5303913, 5303915, 4241301, 4241331, 4241341, 4241781

Abstract:

The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.

US Patent:

7973138, Jul 5, 2011

Filed:

Sep 25, 2008

Appl. No.:

12/237640

Inventors:

Wei-Ching Liang - Foster City CA, US
Gregory D. Plowman - San Carlos CA, US
Yan Wu - Foster City CA, US
Weilan Ye - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C12P 21/08

US Classification:

5303873, 53038885, 5303911, 5303913, 5303917

Abstract:

The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.

US Patent:

8085498, Dec 27, 2011

Filed:

Sep 17, 2009

Appl. No.:

12/586249

Inventors:

Zhigang Bai - Milpitas CA, US
Yue Liu - Fremont CA, US
Kowang Liu - Fremont CA, US
Yan Wu - Cupertino CA, US
Moris Dovek - San Jose CA, US

Assignee:

Headway Technologies, Inc. - Milpitas CA

International Classification:

G11B 5/127

US Classification:

36012503

Abstract:

A PMR writer having a trailing shield structure is disclosed in which a flux choking layer (FCL) formed adjacent to the ABS provides a means to limit the amount of flux flowing from the trailing shield to a first write shield (WS) near the write pole tip thereby significantly reducing adjacent track erasure. The FCL has a substantially smaller thickness than a top section of the trailing shield to which it is attached along a side opposite the ABS. As a result, pole tip protrusion is reduced compared to prior art PMR writers. The FCL contacts a trailing side of WS at the ABS and one or both of the trailing sides of the WS and FCL may be tapered or perpendicular with respect to the ABS. The top trailing shield section, FCL, and WS may be comprised of NiFe, CoFe, CoFeNi, or alloys thereof.

US Patent:

8101365, Jan 24, 2012

Filed:

Jan 4, 2007

Appl. No.:

12/160084

Inventors:

Yan Wu - Foster City CA, US
Minhong Yan - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C12P 21/08
G01N 33/53
C07H 21/04

US Classification:

435 71, 435325, 435334, 435 691, 536 235, 530350, 5303871, 5303873, 53038822, 5303913

Abstract:

The invention provides anti-EphB4 antibodies, and compositions comprising and methods of using these antibodies.

US Patent:

8105705, Jan 31, 2012

Filed:

Oct 26, 2009

Appl. No.:

12/589598

Inventors:

Zhigang Bai - Milpitas CA, US
Yuchen Zhou - San Jose CA, US
Joe Smyth - Aptos CA, US
Moris Dovek - San Jose CA, US
Yan Wu - Cupertino CA, US

Assignee:

Headway Technologies, Inc. - Milpitas CA

International Classification:

G11B 5/127
G11B 5/858

US Classification:

428815, 216 38, 360319

Abstract:

An improved magnetic shield for a perpendicular magnetic write head is disclosed. Its main feature is a pair of tabs at the shield's bottom corners. Said tabs are significantly wider at their point of attachment to the shield than further away from the shield. The end portions of each tab slope upwards (away from the ABS) at an angle of about ten degrees. A process for manufacturing the shield is also disclosed.

US Patent:

8124740, Feb 28, 2012

Filed:

Mar 23, 2010

Appl. No.:

12/729999

Inventors:

Wei-Ching Liang - Foster City CA, US
Gregory D. Plowman - San Carlos CA, US
Yan Wu - Foster City CA, US
Weilan Ye - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 16/00
C07K 16/18

US Classification:

5303873, 53038822

Abstract:

The present invention provides new anti-α5β1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.