Yu Chu Liu

US Patent:

20130209991, Aug 15, 2013

Filed:

Jan 10, 2013

Appl. No.:

13/738658

Inventors:

Northeastern University - , US
Yu Liu - Boston MA, US
Mehmet Remzi Dokmeci - Brookline MA, US

Assignee:

Northeastern University - Boston MA

International Classification:

G01N 27/02
A61B 5/1473
H01L 21/02

US Classification:

435 5, 422 8201, 422 8202, 422430, 436501, 435 71, 4352873, 438 49, 600345

Abstract:

Sensors based on single-walled carbon nanotubes (SWNT) are integrated into a microfluidic system outfitted with data processing and wireless transmission capability. The sensors combine the sensitivity, specificity, and miniature size of SWNT-based nanosensors with the flexible fluid handling power of microfluidic “lab on a chip” analytical systems. Methods of integrating the SWNT-based sensor into a microfluidic system are compatible with the delicate nature of the SWNT sensor elements. The sensor devices are capable of continuously and autonomously monitoring and analyzing liquid samples in remote locations, and are applicable to real time water quality monitoring and monitoring of fluids in living systems and environments. The sensor devices and fabrication methods of the invention constitute a platform technology, because the devices can be designed to specifically detect a large number of distinct chemical agents based on the functionalization of the SWNT. The sensors can be combined into a multiplex format that detects desired combinations of chemical agents simultaneously.

US Patent:

20160129455, May 12, 2016

Filed:

Dec 18, 2015

Appl. No.:

14/974517

Inventors:

- Boston MA, US
Yu Liu - Boston MA, US
Mehmet Remzi Dokmeci - Brookline MA, US

International Classification:

B03C 5/00
G01N 33/18
G01N 27/07

Abstract:

Sensors based on single-walled carbon nanotubes (SWNT) are integrated into a microfluidic system outfitted with data processing and wireless transmission capability. The sensors combine the sensitivity, specificity, and miniature size of SWNT-based nanosensors with the flexible fluid handling power of microfluidic “lab on a chip” analytical systems. Methods of integrating the SWNT-based sensor into a microfluidic system are compatible with the delicate nature of the SWNT sensor elements. The sensor devices are capable of continuously and autonomously monitoring and analyzing liquid samples in remote locations, and are applicable to real time water quality monitoring and monitoring of fluids in living systems and environments. The sensor devices and fabrication methods of the invention constitute a platform technology, because the devices can be designed to specifically detect a large number of distinct chemical agents based on the functionalization of the SWNT. The sensors can be combined into a multiplex format that detects desired combinations of chemical agents simultaneously.

US Patent:

20150272443, Oct 1, 2015

Filed:

Mar 25, 2015

Appl. No.:

14/668574

Inventors:

- St. Paul MN, US
Joseph M. Schmitt - Andover MA, US
Yu Liu - Irvine CA, US

International Classification:

A61B 5/00
A61B 5/02

Abstract:

A single optical fiber force-sensing assembly includes a catheter configured to detect both axial and bending tip displacement. The catheter includes a flexible structure located adjacent to a distal tip portion of the catheter. The single optical fiber within the catheter defines a first reflective surface. A second reflective surface is located closely adjacent to the first reflective surface.