Yuan Yann Chen

US Patent:

7514998, Apr 7, 2009

Filed:

Dec 7, 2006

Appl. No.:

11/636365

Inventors:

Mohammad Mojarradi - La Canada CA, US
Greg Levanas - Costa Mesa CA, US
Yuan Chen - Pasadena CA, US
Raymond S. Cozy - Altadena CA, US
Robert Greenwell - Knoxville TN, US
Stephen Terry - Knoxville TN, US
Benjamin J. Blalock - Knoxville TN, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

H03F 3/45
H01L 35/00
G05F 3/02

US Classification:

330256, 327513, 327539

Abstract:

The present invention relates to a reference current circuit. The reference circuit comprises a low-level current bias circuit, a voltage proportional-to-absolute temperature generator for creating a proportional-to-absolute temperature voltage (VPTAT), and a MOSFET-based constant-IC regulator circuit. The MOSFET-based constant-IC regulator circuit includes a constant-IC input and constant-IC output. The constant-IC input is electrically connected with the VPTAT generator such that the voltage proportional-to-absolute temperature is the input into the constant-IC regulator circuit. Thus the constant-IC output maintains the constant-IC ratio across any temperature range.

US Patent:

20120302815, Nov 29, 2012

Filed:

Feb 21, 2012

Appl. No.:

13/401642

Inventors:

Yuan Chen - Arcadia CA, US
David Horne - Duarte CA, US
Yuelong Ma - Duarte CA, US
Yang Su - Beijing, CN

International Classification:

C07F 1/12
A61L 2/08
A61M 37/00
C12N 5/09

US Classification:

600 1, 556117, 435375, 422 22

Abstract:

A composition used to develop a reagent for investigating Ubl-modifications in cellular functions and in the treatment of cancer is provided. The composition comprises gold nanoparticle (AuNP)-ligand conjugates that include at least two components: gold nanoparticles (AuNPs) and modified ubiquitin- or ubiquitin-like interacting motif (UIM or ULIM) mimetics. In one embodiment, the modified ULM mimetic is a modified SUMO interaction motif (SIM) mimetic. According to the embodiments described herein, the compound inhibits ubiquitin- or ubiquitin-like protein (Ubl)-mediated protein-protein interactions and sensitizes cells to ionizing radiation. The modified UIM and ULIM mimetics may be conjugated to the AuNP such that each AuNP is conjugated to a plurality of modified UIM or ULIM mimetics. The modified ULIM mimetics may be conjugated to the AuNP via a thiol group.

US Patent:

20160026037, Jan 28, 2016

Filed:

Jul 23, 2014

Appl. No.:

14/339263

Inventors:

- Cupertino CA, US
Yuan Chen - Orlando FL, US
Zhibing Ge - Sunnyvale CA, US

International Classification:

G02F 1/1335
G02F 1/1368

Abstract:

A display may have a thin-film transistor layer formed from a layer of thin-film transistor circuitry on a substrate, a color filter layer, and a layer of liquid crystal material interposed between the thin-film transistor layer and the color filter layer. The thin-film transistor layer, the liquid crystal layer, and the color filter layer may be sandwiched between upper and lower polarizers. A backlight unit may supply backlight illumination for pixels in the display. The color filter layer may have a black matrix with an array of openings. Color filter elements of different colors may be formed in the openings. The black matrix may have sidewalls that are steep or that are undercut. The profile of the black matrix helps block improperly colored off-axis light and thereby reduces undesired color mixing in the display.