David Wolf

US Patent:

7247018, Jul 24, 2007

Filed:

May 18, 2004

Appl. No.:

10/848929

Inventors:

George Kantor - Denver CO, US
Paul Ritter Smith - Denver CO, US
Michael Dean Stevens - Littleton CO, US
Daphne Upchurch - Lakewood CO, US
David R. Wolf - Lakewood CO, US
Rosilio Ronald Perez - Vista CA, US

Assignee:

RMO, Inc. - Denver CO

International Classification:

A61C 3/00

US Classification:

433 9

Abstract:

An improved edgewise orthodontic bracket is disclosed. In one embodiment, a bracket comprises a single pair of opposing T-shaped tie wings which define an archwire slot therebetween. Notches are provided on each of the mesial and distal sides of the center leg of each T-shaped tie wing for selectively receiving a ligating device. The notches are defined in the gingival/occlusal edges of the tie wings and comprise sloped portions that extend labially towards the archwire slot. Convex sidewall portions and convex floor portions are provided in the archwire slot adjacent to the notches. The body of the bracket is interconnected to a base that includes a continuous series of characters that serve as texturing to facilitate bonding of the bracket with a tooth. A discontinuous perimeter rail may be used at the edge of the base. A method for forming a bracket is also provided.

US Patent:

20030207796, Nov 6, 2003

Filed:

Apr 3, 2003

Appl. No.:

10/407098

Inventors:

Uma Sinha - San Francisco CA, US
David Wolf - Davis CA, US

Assignee:

Millennium Pharmaceuticals, Inc.

International Classification:

A61K038/17
A61K039/395

US Classification:

514/008000, 424/145100

Abstract:

Reagents that specifically bind a carbohydrate target wherein sialic acid is linked at the nonreducing terminus of a glycoside to a galactose or galactosamine residue through an 2-6 linkage are able to inhibit the conversion of human Factor X to human Factor Xa. These reagents (SA/Gal/GalNAc binding reagents) as well as other strategies for inhibiting the conversion of Factor X to Factor Xa are useful in treating thrombosis, inflammation and other conditions associated with excess thrombin activity.

US Patent:

20070264606, Nov 15, 2007

Filed:

Apr 26, 2007

Appl. No.:

11/740812

Inventors:

Chris Muha - Centennial CO, US
David Wolf - Lakewood CO, US
Daphne Upchurch - Lakewood CO, US
Leon Laub - Fort Collins CO, US
Robert Rudman - Denver CO, US

Assignee:

RMO, INC. - Denver CO

International Classification:

A61C 3/00

US Classification:

433017000

Abstract:

A convertible orthodontic bracket is disclosed, wherein an archwire slot therein has a removable slot covering, thereby allowing the bracket to serve as a buccal tube during a first stage of treatment and an edgewise bracket during a subsequent phase of treatment. The slot covering is removable by detaching the slot covering from the bracket body along one or more predetermined extents of weakness, wherein each such extent of weakness includes perforations or voids providing a passage between an exterior of the bracket and an interior of the first archwire slot.

US Patent:

20080138759, Jun 12, 2008

Filed:

Sep 19, 2007

Appl. No.:

11/858076

Inventors:

Neal D. Kravitz - Fairfax Station VA, US
David Wolf - Lakewood CO, US
Leon W. Laub - Fort Collins CO, US

International Classification:

A61C 7/00

US Classification:

433 21, 433 18, 433 24

Abstract:

An orthodontic appliance for orthodontic treatment includes first and second eyelets connected to coil spring at each end of the coil spring, thereby forming a double eyelet and spring unit. In one embodiment, a connector for detachably attaching a spring to an orthodontic appliance includes a means for engaging an appliance. In one embodiment the connector is an eyelet having an aperture in its central region for allowing the spring to be detachably attached to the orthodontic appliance. The aperture may have a variety of shapes. Alternatively, the connector may comprise a hook or equivalent structure for facilitating the spring to be attached to the orthodontic appliance.

US Patent:

20080160474, Jul 3, 2008

Filed:

Apr 2, 2007

Appl. No.:

11/695555

Inventors:

David Wolf - Lakewood CO, US
Tony Zakhem - Highlands Ranch CO, US
Leon Laub - Fort Collins CO, US
Michael Stevens - Littleton CO, US
George Kantor - Denver CO, US

Assignee:

RMO, INC. - Denver CO

International Classification:

A61C 7/14
A61C 7/28

US Classification:

433 10

Abstract:

A triple wing orthodontic bracket, bracket cover, and method of use is disclosed. The bracket has a slot liner for reducing friction between an archwire and the bracket, wherein the liner is flared at its ends. The bracket cover has: a rod-shaped hinge for rotating in recesses between a bracket base, and bracket wings on one of a gingival and occlusal bracket side, a slot cover, and a cross member for rotating the slot cover between covering a bracket archwire slot, and uncovering the slot, wherein the rotation pivots the hinge in the recesses. The hinge and recesses frictionally engage one another, wherein in a first position, the hinge attaches and detaches from the bracket, and after pivoting the hinge to another position in the recesses, the hinge is secured therein. Interaction between the hinge and the recesses may cause the slot cover to move to cover the slot.

US Patent:

57983321, Aug 25, 1998

Filed:

Sep 6, 1994

Appl. No.:

8/302226

Inventors:

Uma Sinha - San Francisco CA
David L. Wolf - Palo Alto CA

Assignee:

COR Therapeutics, Inc. - South San Francisco CA

International Classification:

A61K 3816
A61K 3836
A61K 3843

US Classification:

514 8

Abstract:

Reagents that specifically bind a carbohydrate target wherein sialic acid is linked at the nonreducing terminus of a glycoside to a galactose or galactosamine residue through an. alpha. 2-6 linkage are able to inhibit the conversion of human Factor X to human Factor Xa. These reagents (SA/Gal/GalNAc binding reagents) as well as other strategies for inhibiting the conversion of Factor X to Factor Xa are useful in treating thrombosis, inflammation and other conditions associated with excess thrombin activity.

US Patent:

61178365, Sep 12, 2000

Filed:

Dec 2, 1994

Appl. No.:

8/307609

Inventors:

Uma Sinha - San Francisco CA
David L. Wolf - Palo Alto CA

Assignee:

COR Therapeutics, Inc. - South San Francisco CA

International Classification:

A61K 3800
A61K 39395
C07K 400
C07K 1618

US Classification:

514 2

Abstract:

Reagents that specifically bind a carbohydrate target wherein sialic acid is linked at the nonreducing terminus of a glycoside to a galactose or galactosamine residue through an. alpha. 2-6 linkage are able to inhibit the conversion of human Factor X to human Factor Xa. These reagents (SA/Gal/GalNAc binding reagents) as well as other strategies for inhibiting the conversion of Factor X to Factor Xa are useful in treating thrombosis, inflammation and other conditions associated with excess thrombin activity.