Linda N Pham

US Patent:

20230041283, Feb 9, 2023

Filed:

May 24, 2022

Appl. No.:

17/752703

Inventors:

- North Chicago IL, US
Joel N. Jimenez Lozano - Dublin CA, US
Like Zeng - North Chicago IL, US
George Frangineas, JR. - Fremont CA, US
Linda Pham - Pleasanton CA, US

International Classification:

A61F 7/00
A61K 9/06
A61K 9/00

Abstract:

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

US Patent:

20210038278, Feb 11, 2021

Filed:

Oct 15, 2020

Appl. No.:

17/072020

Inventors:

- Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Kristine Tatsutani - Redwood City CA, US
Linda Pham - Kensington CA, US

International Classification:

A61B 18/02
A61F 7/00
A61H 1/00
A61N 7/00
A61K 31/045
A61K 31/047
A61B 90/00

Abstract:

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

US Patent:

20200138501, May 7, 2020

Filed:

Jan 7, 2020

Appl. No.:

16/736672

Inventors:

- Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Kristine Tatsutani - Redwood City CA, US
Bryan J. Weber - Livermore CA, US
Kerrie Jiang - Foster City CA, US
Peter Yee - San Ramon CA, US
Linda Pham - Pleasanton CA, US
Gurvinder Singh Nanda - Fremont CA, US

International Classification:

A61B 18/02
A61B 90/00
A61K 31/047
A61K 31/045
A61F 7/00
A61H 1/00
A61N 7/00

Abstract:

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

US Patent:

20200038234, Feb 6, 2020

Filed:

Jul 31, 2019

Appl. No.:

16/528249

Inventors:

- Pleasanton CA, US
Like Zeng - Pleasanton CA, US
Linda Pham - Kensington CA, US
George Frangineas, Jr. - Fremont CA, US

International Classification:

A61F 7/00

Abstract:

Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

US Patent:

20190142493, May 16, 2019

Filed:

Dec 20, 2018

Appl. No.:

16/227376

Inventors:

- Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Kristine Tatsutani - Redwood City CA, US
Linda Pham - Kensington CA, US

International Classification:

A61B 18/02
A61F 7/00
A61K 31/045
A61K 31/047
A61H 1/00
A61N 7/00
A61B 90/00

Abstract:

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance sites with cellulite. Treatments can include cooling a surface of a patient's skin and detecting freezing in the cooled skin. The tissue can be cooled after the freeze event is detected so to maintain the frozen state of the tissue to improve the appearance of the treatment site.

US Patent:

20190125424, May 2, 2019

Filed:

Dec 27, 2018

Appl. No.:

16/233951

Inventors:

- Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Kristine Tatsutani - Redwood City CA, US
Linda Pham - Kensington CA, US

International Classification:

A61B 18/02
A61F 7/00
A61K 31/045
A61K 31/047
A61H 1/00
A61N 7/00
A61B 90/00
A61B 18/00

Abstract:

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

US Patent:

20170325992, Nov 16, 2017

Filed:

Apr 27, 2017

Appl. No.:

15/499534

Inventors:

- Pleasanton CA, US
Joel N. Jimenez Lozano - Dublin CA, US
Like Zeng - Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Linda Pham - Pleasanton CA, US

International Classification:

A61F 7/00
A61K 9/06
A61K 9/00
A61M 37/00
A61F 7/00
A61F 7/00
A61F 7/00
A61F 7/00

Abstract:

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

US Patent:

20170007309, Jan 12, 2017

Filed:

Jan 30, 2015

Appl. No.:

15/115503

Inventors:

- Pleasanton CA, US
George Frangineas, JR. - Fremont CA, US
Kristine Tatsutani - Redwood City CA, US
Bryan J. Weber - Livermore CA, US
Kerrie Jiang - Foster City CA, US
Peter Yee - San Ramon CA, US
Linda Pham - Pleasanton CA, US
Gurvinder Singh Nanda - Fremont CA, US

International Classification:

A61B 18/02
A61B 90/00
A61N 7/00
A61F 7/00
A61H 1/00

Abstract:

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.