Russell L Miller

US Patent:

7842496, Nov 30, 2010

Filed:

May 2, 2007

Appl. No.:

11/797354

Inventors:

Russell G. Miller - Gambrills MD, US
Edward T. Mallinson - Silver Spring MD, US

Assignee:

University of Maryland - College Park MD

International Classification:

C12N 1/20
C12N 1/00

US Classification:

4352536, 435 34, 4352521, 4352524, 435879

Abstract:

Selective growth media N4 agars that include a combination of high levels of yeast extract, possibly higher levels of protein, elevated levels of sugar and reduced levels of sodium chloride. The combination of ingredients provides the ability to detect spp. and spp. with almost identical sensitivity while alleviating false-negative and false-positive problems commonly encountered with the presence of spp. and spp.

US Patent:

52524957, Oct 12, 1993

Filed:

Mar 19, 1992

Appl. No.:

7/853850

Inventors:

Russell L. Miller - Washington DC
Pritam S. Verma - Adelphi MD

Assignee:

Howard University - Washington DC

International Classification:

G01N 33531
G01N 33534
G01N 3353
A61K 3514

US Classification:

436542

Abstract:

A radioimmunoassay for physostigmine in biological fluids. The method disclosed can detect 100 pg of physostigmine per ml of biological fluid using 0. 1 ml of biological fluid. The antibody used in this method can be raised from an antigen produced by either or two methods--diazotizing para-aminobenzoic acid and reacting the diazotized material with physostigmine to form a physostigmine-hapten solution, which is then reacted with bovine serum albumin or by using a Mannich reaction to directly conjugate physostigmine to bovine serum albumin. The antibody used in the disclosed method has a cross-reactivity with the major metabolites of physostigmine of less than 1%.

US Patent:

58719440, Feb 16, 1999

Filed:

Jul 2, 1997

Appl. No.:

8/887274

Inventors:

Russell G. Miller - Gambrills MD
Edward Mallinson - Columbia MD

Assignee:

The University of Maryland - College Park MD

International Classification:

G01N 33569
C12N 120

US Classification:

435 735

Abstract:

A new Salmonella preferential media uses lactose and cellobiose to suppress formation of black colonies by non-Salmonella, to permit easy inspection of the media to determine the presence or absence of Salmonella. Modified media, including high levels of peptone, beef extract, and tris buffers are required for preferential detection of S. typhi, all other Salmonella and Shigella.

US Patent:

52683087, Dec 7, 1993

Filed:

Apr 10, 1989

Appl. No.:

7/335590

Inventors:

Russell L. Miller - Washington DC

Assignee:

Howard University - Washington DC

International Classification:

G01N 33531
G01N 33534
G01N 3353
A61K 3514

US Classification:

436542

Abstract:

A radioimmunoassay for pyridostigmine in biological fluids. The method disclosed can detect 250 pg of pyridostigmine per ml of biological fluid using 0. 1 ml of biological fluid. The antibody used in this method is raised from an antigen produced by diazotizing para-aminobenzoic acid and reacting the diazotized material with pyridostigmine to form a pyridostigmine-hapten solution, which is then reacted with bovine serum albumen. The antibody used in the disclosed method has a cross-reactivity with the major metabolites of pyridostigmine of less than 2%.