Stephanie M Reed

US Patent:

20230126744, Apr 27, 2023

Filed:

Oct 25, 2022

Appl. No.:

18/049535

Inventors:

- Telford PA, US
Scott RADZINSKI - Gilbertsville PA, US
Brian GINN - Harleysville PA, US
Peter D. GABRIELE - Frisco TX, US
Stephanie REED - Conshohocken PA, US
Benjamin ROADARMEL - QUAKERTOWN PA, US

International Classification:

A61K 9/16
A61K 31/7105
A61K 31/711

Abstract:

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

US Patent:

20190231511, Aug 1, 2019

Filed:

Jan 31, 2019

Appl. No.:

16/264087

Inventors:

- Telford PA, US
Amanda WEBER - Macungie PA, US
Andrew METZGER - Lafayette Hill PA, US
Stephanie REED - Conshohocken PA, US
Carissa SMOOT - Harleysville PA, US

International Classification:

A61F 2/07
A61F 2/00

Abstract:

The disclosure describes textiles for endovascular and other medical applications having a low-profile and varying density. The textiles are woven and are formed of a non-uniform construction. The resulting textiles have a low profile and areas of targeted density to enhance ingrowth of regenerative tissue.