Materials Science Thin Films Characterization Surface Analysis Mass Spectrometry Design of Experiments Nanotechnology Research and Development Failure Analysis Semiconductors
Fosun Kite
Director, Product Science and Process Development
Berkeley Lights, Inc.
Director, Biology and Point of Care Therapeutics
Berkeley Lights, Inc. Sep 2014 - Jun 2015
Senior Research Biologist
Albert Einstein College of Medicine Mar 2011 - Aug 2014
Research Associate
St. Jude Children's Research Hospital Jan 2010 - Feb 2011
Research Associate
Education:
University of Wisconsin - Madison 2004 - 2009
Doctorates, Doctor of Philosophy, Immunology
University of Wisconsin - Madison 2000 - 2004
Doctorates, Doctor of Philosophy
Fudan University 2001 - 2004
Masters, Immunology
Fudan University 1999 - 2001
Associates, Computer Science
Fudan University 1997 - 2001
Bachelors, Genetics
Skills:
Cell Molecular Biology Cell Biology Cell Culture Flow Cytometry Biochemistry Western Blotting Cell Signaling Pcr Immunology Antibodies Molecular Cloning Stem Cells Assay Development Animal Models Fluorescence Microscopy Cancer Research Laboratory Confocal Microscopy Qpcr Tissue Culture Elisa Protein Expression Rt Pcr Immunohistochemistry Virology In Vivo Cancer Microscopy Translational Research Immunoassays Protein Purification Immunofluorescence Dna Life Sciences Biotechnology High Throughput Screening Cancer Immunotherapy Cell Therapy Microfluidics Reverse Transcription Polymerase Chain Reaction Polymerase Chain Reaction Real Time Polymerase Chain Reaction
Interests:
System Immune Biology T Cell Activation and Tolerance Cell Biology Antibody Diversification Immune Cell Differentiation Immune Homeostasis
Languages:
Mandarin English
Certifications:
Regulatory Affairs Certificate: Medical Devices and Pharmaceuticals (Dual)
Joann Fabric & Craft Store Inc. Hudson, OH Aug 2011 to Sep 2012 Sr. Product Development & Sourcing SpecialistKeeco LLC Hayward, CA May 2010 to May 2011 Product Development ManagerBig Buddha Inc Santa Cruz, CA Sep 2009 to Feb 2010 Director of ProductionE & E Co., Ltd Fremont, CA Jan 2006 to Oct 2008 Product/Production ManagerVictoria Classics New York, NY Jan 2005 to Dec 2005 Production CoordinatorShanghai Hansen Imp. & Exp. Co., Ltd
Jul 1993 to Jan 2005 Senior Merchandiser
Education:
Shanghai University 1989 to 1993 Bachelor of Arts in International Trade
Skills:
Microsoft (Word, Excel, Outlook, Power Point)
Us Patents
In-Situ Generated Microfluidic Assay Structures, Related Kits, And Methods Of Use Thereof
- Emeryville CA, US Peter J. BEEMILLER - Emeryville CA, US Volker L.S. KURZ - Oakland CA, US Gregory G. LAVIEU - Emeryville CA, US Xiaohua WANG - Albany CA, US Aathavan KARUNAKARAN - Berkeley CA, US
Assignee:
BERKLEY LIGHTS, INC. - Emeryville CA
International Classification:
G01N 33/543 B01L 3/00 G01N 33/545 G01N 33/58
Abstract:
In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.
Microfluidic Devices For Optically-Driven Convection And Displacement, Kits And Methods Thereof
- Emeryville CA, US Troy A. Lionberger - Berkeley CA, US Eric K. Sackmann - Oakland CA, US Kai W. Szeto - Emeryville CA, US Paul M. Lebel - San Mateo CA, US Brandon R. Bruhn - San Francisco CA, US Keith J. Breinlinger - San Rafael CA, US Eric D. Hobbs - Livermore CA, US Andrew W. McFarland - Berkeley CA, US J. Tanner Nevill - El Cerrito CA, US Xiaohua Wang - Albany CA, US
International Classification:
C12M 3/06 B01L 3/00 C12M 1/00 C12M 1/26
Abstract:
Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
- Emeryville CA, US - Oakland CA, US Payal Watchmaker - San Francisco CA, US Yelena Bronevetsky - Alameda CA, US Ryosuke Naka - San Francisco CA, US Guido K. Stadler - San Francisco CA, US Xiaohua Wang - Pomona NY, US Kevin T. Chapman - Emeryville CA, US
Assignee:
Berkeley Lights, Inc. - Emeryville CA The Regents of the University of California - Oakland CA
International Classification:
C07K 14/725 C12N 5/0783 C12N 15/63
Abstract:
This disclosure relates to the production and use of an isolated, purified and/or recombinant T cell receptor (TCR) that specifically binds to a mutant IDH1 protein, or a fragment thereof, wherein the mutant IDH1 protein or fragment thereof comprises an R132H mutation.
Microfluidic Reporter Cell Assay Methods And Kits Thereof
- Emeryville CA, US Mark P. White - San Francisco CA, US Jason M. McEwen - El Cerrito CA, US Gang F. Wang - Mountain View CA, US Kevin T. Chapman - Santa Monica CA, US Xiaohua Wang - Albany CA, US Christine E. Sun - Emeryville CA, US
Functional assays using reporter cell assays are described which probe the activity of at least one cell of interest. The ability to probe at least one cell is provided by using the microfluidic methods, devices and kits described herein. Assays combining both reporter cell signaling as well as binding assay signaling for at least one cell is also described herein.
In Situ-Generated Microfluidic Assay Structures, Related Kits, And Methods Of Use Thereof
- Emeryville CA, US Peter J. Beemiller - Emeryville CA, US Volker L.S. Kurz - Oakland CA, US Gregory G. Lavieu - Emeryville CA, US Xiaohua Wang - Albany CA, US Aathavan Karunakaran - Berkeley CA, US
International Classification:
G01N 33/543 B01L 3/00 G01N 33/545 G01N 33/58
Abstract:
In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.
Methods Of Producing Patient-Specific Anti-Cancer Therapeutics And Methods Of Treatment Therefor
- Emeryville CA, US Mark P. White - Orinda CA, US Xiaohua Wang - Pomona NY, US Minha Park - Brisbane CA, US Guido K. Stadler - San Francisco CA, US Xiao Guan Radstrom - San Rafael CA, US Jason M. McEwen - El Cerrito CA, US Gang F. Wang - Mountain View CA, US George L. Fox - Albany CA, US Peggy A. Radel - Berkeley CA, US
A method of preparing an antibody therapeutic is provided comprising: (a) providing a dissociated cell sample from at least one solid tumor sample obtained from a patient; (b) loading the dissociated cell sample into a microfluidic device having a flow region and at least one isolation region fluidically connected to the flow region; (c) moving at least one B cell from the dissociated cell sample into at least one isolation region in the microfluidic device, thereby obtaining at least one isolated B cell; and (d) using the microfluidic device to identify at least one B cell that produces antibodies capable of binding to cancer cells. The cancer cells can be the patient's own cancer cells. Also provided are methods of treating patients, methods of labeling or detecting cancer, engineered T or NK cells comprising antibodies or fragments thereof, and engineered antibody constructs.
- Emeryville CA, US Yelena Bronevetsky - San Francisco CA, US Peter J. Beemiller - Emeryville CA, US Xiaohua Wang - Albany CA, US Kevin T. Chapman - Santa Monica CA, US
International Classification:
B01L 3/00 G01N 1/34 A61K 35/17
Abstract:
Methods of sorting T lymphocytes in a microfluidic device are provided. The methods can include flowing a fluid sample comprising T lymphocytes through a region of a microfluidic device that contains an array of posts. The array of posts can be configured to have a critical size (D) that separates activated T lymphocytes from naïve T lymphocytes. Also provided are microfluidic devices having an array of posts configured to separate activated T lymphocytes from naïve T lymphocytes, compositions enriched for T lymphocytes, particularly activated T lymphocytes that are known to be reactive to an antigen of interest, and methods of treating subjects suffering from a pathogenic disorder or cancer by administering such compositions.
Microfluidic Devices For Optically-Driven Convection And Displacement, Kits And Methods Thereof
- Emeryville CA, US Troy A. Lionberger - Berkeley CA, US Erik K. Sackmann - Oakland CA, US Kai W. Szeto - Emeryville CA, US Paul M. Lebel - San Mateo CA, US Brandon R. Bruhn - San Francisco CA, US Keith J. Breinlinger - San Rafael CA, US Eric D. Hobbs - Livermore CA, US Andrew W. McFarland - Berkeley CA, US J. Tanner Nevill - El Cerrito CA, US Xiaohua Wang - Albany CA, US
International Classification:
C12M 3/06 B01L 3/00 C12M 1/00 C12M 1/26
Abstract:
Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
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Youtube
Xiaohua Wang IDA AGM 2013
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21m 10s
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