Aaron J Richardson

US Patent:

20210332400, Oct 28, 2021

Filed:

Oct 3, 2019

Appl. No.:

16/592707

Inventors:

- Healdsburg CA, US
Josephine Lee - Hayward CA, US
Pranav Patel - Fremont CA, US
Aaron Richardson - Palo Alto CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12P 19/34
C12Q 1/686

Abstract:

Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases and primers.

US Patent:

20210147910, May 20, 2021

Filed:

Oct 29, 2020

Appl. No.:

17/083815

Inventors:

- Healdsburg CA, US
Indira Wu - San Jose CA, US
Aaron Richardson - Palo Alto CA, US
Zahra Kamila Belhocine - Fremont CA, US
Josephine Lee - Hayward CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12Q 1/686
C12Q 1/6806

Abstract:

Improved methods for amplifying target nucleic acid sequences are provided by 1) first amplifying the number of copies of target nucleic acid sequences in a sample by a first nucleic acid amplification method, and then 2) applying a second nucleic amplification method to the amplified sample, or aliquot thereof, further amplifying the number of copies of target sequences. In embodiments, a first nucleic acid amplification method is a thermocycling method, and a second nucleic acid amplification method is an isothermal method.

US Patent:

20210024987, Jan 28, 2021

Filed:

Aug 6, 2020

Appl. No.:

16/986557

Inventors:

- Healdsburg CA, US
Josephine Lee - Hayward CA, US
Pranav Patel - Fremont CA, US
Aaron Richardson - Palo Alto CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12Q 1/6844
C12P 19/34
C12Q 1/686
C07H 1/00

Abstract:

Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such nucleic acid polymerases and primers.

US Patent:

20200013488, Jan 9, 2020

Filed:

Apr 12, 2019

Appl. No.:

16/382593

Inventors:

- Healdsburg CA, US
Elizabeth A. Holmes - San Francisco CA, US
Pranav Patel - Fremont CA, US
Scott Tabakman - Palo Alto CA, US
Zahra Kamila Belhocine - Fremont CA, US
Aaron Richardson - Palo Alto CA, US
Josephine Lee - Hayward CA, US

International Classification:

G16H 10/40
G01N 35/10
C12Q 1/70
G01N 33/569
C12Q 1/6895
C12Q 1/6893
C12Q 1/689

Abstract:

Systems, methods, and devices for detecting infections in a clinical sample are provided. Small-volume clinical samples obtained at a point-of-service (POS) location and may be tested at the POS location for multiple markers for multiple diseases, including upper and lower respiratory diseases. Samples may be tested for cytokines, or for inflammation indicators. Dilution of samples, or levels of detection, may be determined by the condition or past history of a subject. Test results may be obtained within a short amount of time after sample placement in a testing device, or within a short amount of time after being obtained from the subject. A prescription for treatment of a detected disorder may be provided, and may be filled, at the POS location. A bill may be automatically generated for the testing, or for the prescription, may be automatically sent to an insurance provider, and payment may be automatically obtained.

US Patent:

20190203278, Jul 4, 2019

Filed:

Nov 14, 2018

Appl. No.:

16/190625

Inventors:

- Healdsburg CA, US
Josephine Lee - Hayward CA, US
Pranav Patel - Fremont CA, US
Aaron Richardson - Palo Alto CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12Q 1/6844
C07H 1/00
C12P 19/34
C12Q 1/686

Abstract:

Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases and primers.

US Patent:

20180223381, Aug 9, 2018

Filed:

Jan 26, 2018

Appl. No.:

15/881375

Inventors:

- Newark CA, US
Indira Wu - San Jose CA, US
Aaron Richardson - Palo Alto CA, US
Zahra Kamila Belhocine - Fremont CA, US
Josephine Lee - Hayward CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12Q 1/70
C12Q 1/6858

Abstract:

Methods and compositions for the identification of genetic-related information are provided. At least portions of methods provided herein may be performed without thermocycling. Methods and compositions may include reagents such as nucleic acid polymerases and primers.

US Patent:

20180094306, Apr 5, 2018

Filed:

Jul 6, 2017

Appl. No.:

15/642746

Inventors:

- Palo Alto CA, US
Josephine Lee - Hayward CA, US
Pranav Patel - Fremont CA, US
Aaron Richardson - Palo Alto CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12P 19/34
C07H 1/00

Abstract:

Methods and compositions for the amplification of nucleic acids and generation of concatemers are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such nucleic acid polymerases and primers.

US Patent:

20170342476, Nov 30, 2017

Filed:

Mar 14, 2017

Appl. No.:

15/458528

Inventors:

- Palo Alto CA, US
Indira Wu - San Jose CA, US
Aaron Richardson - Palo Alto CA, US
Zahra Kamila Belhocine - Fremont CA, US
Josephine Lee - Hayward CA, US
Scott Tabakman - Palo Alto CA, US

International Classification:

C12Q 1/68
C12M 1/00
C12Q 1/70
C12N 15/00

Abstract:

Improved methods for amplifying target nucleic acid sequences are provided by 1) first amplifying the number of copies of target nucleic acid sequences in a sample by a first nucleic acid amplification method, and then 2) applying a second nucleic amplification method to the amplified sample, or aliquot thereof, further amplifying the number of copies of target sequences. In embodiments, a first nucleic acid amplification method is a thermocycling method, and a second nucleic acid amplification method is an isothermal method.