Valentino J. Stella - Lawrence KS Abraham E. Mathew - Lenexa KS
Assignee:
University of Kansas - Lawrence KS
International Classification:
A61K 31335 C07D30514
US Classification:
514449
Abstract:
Derivatives of taxol represented by the formula ##STR1## wherein R and R' are each H or the residue of an amino acid selected from the group consisting of alanine, leucine, isoleucine, saline, phenylalanine, proline, lysine and arginine or a group of the formula ##STR2## wherein n is an integer of 1 to 3 and R. sup. 2 and R. sup. 3 are each hydrogen on an alkyl radical having from one to three carbon atoms or wherein R. sup. 2 and R. sup. 3 together with the nitrogen atom to which they are attached form a saturated heterocyclic ring having four to five carbon atoms, with the proviso that at least one of R and R. sup. 1 is not hydrogen, are provided together with pharmaceutical compositions of such derivatives. The taxol derivatives have increased water solubility as compared to taxol, and have excellent antitumor activity.
Isbn (Books And Publications)
Role of Panchayats in Welfare Administration: A Study with Special Reference to Centrally Sponsored Schemes
Aug 2010 to 2000 Client Operations, AssociateKeller & Owens Overland Park, KS Sep 2008 to May 2010 InternshipHis Grace Enterprise Olathe, KS May 2005 to Apr 2008 Assistant Manager
Education:
MidAmerica Nazarene University May 2010 Bachelor of Science in Accounting
Name / Title
Company / Classification
Phones & Addresses
Abraham P. Mathew President
Eagle Business Brokers LLC Real Estate Agent/Manager
3443 S Galena St, Denver, CO 80231
Abraham P. Mathew President
Pak-Mail Senders of America Business Services
8601 W Cross Dr, Littleton, CO 80123 (303)9710088
Abraham P. Mathew President
Robby & Ryan, Inc Business Services
8601 W Cross Dr, Littleton, CO 80123 (303)9710088
Abraham Mathew CEO
Glen Oaks Realty
8910 N Central Ave, Phoenix, AZ 85020 (718)3472600
Acute Pancreatitis Cholelethiasis or Cholecystitis Inflammatory Bowel Disease (IBD) Benign Polyps of the Colon Chronic Pancreatitis
Languages:
English Spanish
Description:
Dr. Mathew graduated from the Kottayam Med Coll, Mahatma Gandhi Univ, Kottayam, Kerala, India in 1994. He works in Hershey, PA and 1 other location and specializes in Gastroenterology. Dr. Mathew is affiliated with Penn State Milton S Hershey Medical Center.
Dr. Mathew graduated from the Univ of Jos, Fac of Med Sci, Jos, Plateau, Nigeria in 1985. He works in Finksburg, MD and specializes in Family Medicine.
Abraham P Mathew MD 3330 W 177 St STE 1G, Hazel Crest, IL 60429 (708)6875400 (phone), (708)9602459 (fax)
Education:
Medical School Rush Medical College Graduated: 1987
Languages:
English Spanish
Description:
Dr. Mathew graduated from the Rush Medical College in 1987. He works in Hazel Crest, IL and specializes in Internal Medicine. Dr. Mathew is affiliated with Advocate South Suburban Hospital.