Ada L Rivera

US Patent:

7927626, Apr 19, 2011

Filed:

Jul 21, 2004

Appl. No.:

10/896454

Inventors:

Sanyog M. Pendharkar - Old Bridge NJ, US
Anne J. Gorman - Highstown NJ, US
Guanghui Zhang - Belle Mead NJ, US
Ada Rivera - Hillsborough NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61K 9/14
C12N 9/74
C12Q 1/56
A01N 37/18

US Classification:

424489, 435214, 435 13, 514 2

Abstract:

The present invention is directed to processes of making flowable hemostatic compositions and devices that include the flowable hemostatic composition disposed therein, where a volume of a biocompatible liquid, a volume of a biocompatible gas, and an amount of solid particles of a biocompatible polymer are mixed together to form a substantially homogenous composition including a discontinuous gas phase and the solid particles substantially homogenously dispersed throughout a continuous liquid phase to form a flowable hemostatic composition, and the composition then transferred into a device suitable for applying the flowable hemostatic composition to a site of a body requiring hemostasis under conditions effective to maintain the substantially homogeneous dispersion of the gas phase and the solid particles throughout the liquid phase.

US Patent:

8551941, Oct 8, 2013

Filed:

Oct 11, 2010

Appl. No.:

12/902017

Inventors:

Sanyog M. Pendharkar - Edison NJ, US
Anne J. Gorman - Hightstown NJ, US
Guanghui Zhang - Belle Mead NJ, US
Ada Rivera - Neshanic Station NJ, US
Dwayne Lee Looney - Flemington NJ, US
Thomas Lee Craven - Bridgewater NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61K 38/00
A61K 38/48

US Classification:

514 2, 424 9464

Abstract:

The present invention includes both sterilized and unsterilized hemostatic compositions that contain a continuous, biocompatible liquid phase having a solid phase of particles of a biocompatible polymer suitable for use in hemostasis and which is substantially insoluble in the liquid phase, and a discontinuous, biocompatible gaseous phase, each of which is substantially homogenously dispersed throughout the continuous liquid phase, methods for making such compositions, medical devices that contain sterilized hemostatic compositions disposed therein and methods of making such devices.

US Patent:

20060127488, Jun 15, 2006

Filed:

Feb 7, 2006

Appl. No.:

11/348860

Inventors:

Sanyog Pendharkar - Edison NJ, US
Anne Gorman - Hightstown NJ, US
Guanghui Zhang - Belle Mead NJ, US
Ada Rivera - Neshanic Station NJ, US
Dwayne Looney - Flemington NJ, US
Thomas Craven - Bridgewater NJ, US

International Classification:

A61K 38/39
A61K 9/14
A61K 38/48

US Classification:

424489000, 514021000, 424094640

Abstract:

The present invention includes both sterilized and unsterilized hemostatic compositions that contain a continuous, biocompatible liquid phase having a solid phase of particles of a biocompatible polymer suitable for use in hemostasis and which is substantially insoluble in the liquid phase, and a discontinuous, biocompatible gaseous phase, each of which is substantially homogenously dispersed throughout the continuous liquid phase, methods for making such compositions, medical devices that contain sterilized hemostatic compositions disposed therein and methods of making such devices.