Adam Yuh Lin

US Patent:

8551333, Oct 8, 2013

Filed:

Apr 7, 2008

Appl. No.:

12/594179

Inventors:

Adam Yuh Lin - Irvine CA, US
Tak Sing Wong - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

B03C 1/02
C12M 1/00

US Classification:

210222, 252 6251 R, 422 681, 422502, 422504, 422527, 4352872, 4353081, 436526, 436806

Abstract:

A microfluidic device for manipulating particles in a fluid has a device body that defines a main channel therein, in which the main channel has an inlet and an outlet. The device body further defines a particulate diverting channel therein, the particulate diverting channel being in fluid connection with the main channel between the inlet and the outlet of the main channel and having a particulate outlet. The microfluidic device also has a plurality of microparticles arranged proximate or in the main channel between the inlet of the main channel and the fluid connection of the particulate diverting channel to the main channel. The plurality of microparticles each comprises a material in a composition thereof having a magnetic susceptibility suitable to cause concentration of magnetic field lines of an applied magnetic field while in operation. A microfluidic particle-manipulation system has a microfluidic particle-manipulation device and a magnet disposed proximate the microfluidic particle-manipulation device.

US Patent:

20180355411, Dec 13, 2018

Filed:

Apr 3, 2018

Appl. No.:

15/944586

Inventors:

- Houston TX, US
Richard G. BARANIUK - Houston TX, US
Amirali AGHAZADEH - Houston TX, US
Mona SHEIKH - Redwood City CA, US
Adam Y. LIN - Chicago IL, US
Allen L. CHEN - Silver Spring MD, US
Pallavi BUGGA - Houston TX, US

Assignee:

WILLIAM MARSH RICE UNIVERSITY - Houston TX

International Classification:

C12Q 1/689

Abstract:

The present disclosure is directed to compositions and methods present a universal microbial diagnostic (UMD) platform to screen for microbial organisms in a sample using a small number of random DNA probes that are agnostic to the target DNA sequences. The UMD platform can be used to direct and monitor appropriate treatments, thus minimizing the risk of antibiotic resistance, and enhancing patient care.

US Patent:

20140086828, Mar 27, 2014

Filed:

May 31, 2011

Appl. No.:

13/700582

Inventors:

Aaron E. Foster - Houston TX, US
Laura B. Carpin - Houston TX, US
Adham S. Bear - Houston TX, US
Rebekah Drezek - Spring TX, US
Adam Yuh Lin - Houston TX, US

International Classification:

A61K 47/48
A61K 49/00
A61K 51/12

US Classification:

424 117, 424 9371, 424 9321, 424 96, 424489

Abstract:

The present invention concerns methods and compositions utilizing gold nanoparticles for therapy for a medical condition, such as cancer. In particular aspects, the nanoparticles are included with or in a T cell to facilitate targeting of the nanoparticles to a desired location in vivo and/or to facilitate therapeutic treatment for the condition. In specific cases, the nanoparticle/T cell compositions further comprise microRNAs and/or peptides, and so forth.