Adrian Edward Rice

US Patent:

20210260175, Aug 26, 2021

Filed:

Apr 26, 2021

Appl. No.:

17/240285

Inventors:

- Seattle WA, US
Adrian Rice - Seattle WA, US
Elizabeth Gabitzsch - Seattle WA, US
Yvette Latchman - Seattle WA, US
Joseph Balint - Seattle WA, US

International Classification:

A61K 39/00
A61P 35/00
A61K 39/39
C12N 15/86

Abstract:

Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.

US Patent:

20200171140, Jun 4, 2020

Filed:

Jul 14, 2017

Appl. No.:

16/317739

Inventors:

- Seattie WA, US
Joseph BALINT - Seattle WA, US
Adrian RICE - Seattle WA, US
Yvette LATCHMAN - Seattle WA, US
Elizabeth GABITZSCH - Seattle WA, US

Assignee:

ETUBICS CORPORATION - Seattle WA

International Classification:

A61K 39/12
C12N 15/86

Abstract:

Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.

US Patent:

20200172925, Jun 4, 2020

Filed:

Jul 14, 2017

Appl. No.:

16/317747

Inventors:

- Seattle WA, US
Joseph BALINT - Seattle WA, US
Adrian RICE - Seattle WA, US
Yvette LATCHMAN - Seattle WA, US
Elizabeth GABITZSCH - Seattle WA, US

Assignee:

ETUBICS CORPORATION - Seattle WA

International Classification:

C12N 15/86
C12N 7/00
A61K 39/12
A61P 31/14

Abstract:

Compositions of a recombinant adenovirus based vector vaccine containing one or more alphavirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate broad based immune responses against alphaviruses are also described. Compositions described herein allow for vaccinations in individuals with preexisting immunity to adenovirus.

US Patent:

20200155662, May 21, 2020

Filed:

May 25, 2018

Appl. No.:

16/614909

Inventors:

- Seattle WA, US
Adrian RICE - Seattle WA, US
Elizabeth GABITZSCH - Seattle WA, US
Yvette LATCHMAN - Seattle WA, US
Joseph BALINT - Seattle WA, US

International Classification:

A61K 39/00
A61K 39/39
C12N 15/86
A61P 35/00

Abstract:

Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.

US Patent:

20190125852, May 2, 2019

Filed:

Jun 2, 2017

Appl. No.:

16/306097

Inventors:

- Seattle WA, US
Joseph BALINT - Seattle WA, US
Yvette LATCHMAN - Seattle WA, US
Adrian RICE - Seattle WA, US
Elizabeth GABITZSCH - Seattle WA, US

International Classification:

A61K 39/00
C12N 15/86
A61P 35/00

Abstract:

Methods and compositions for constructing and producing recombinant adenovirus-based vector vaccines are provided. In particular aspects, there are be provided compositions and methods involving adenovirus vectors comprising genes for target antigens, such as pro state-specific antigen (PSA), pro state-specific membrane antigen (PSMA), MUC1, CEA, and/or Brachyury, and costimulatory molecules for use in treatment methods that generate highly reactive anti-tumor immune responses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus.

US Patent:

20190030151, Jan 31, 2019

Filed:

Jan 13, 2017

Appl. No.:

16/070201

Inventors:

- Seattle WA, US
Elizabeth Gabitzsch - Seattle WA, US
Yvette Latchman - Seattle WA, US
Adrian Rice - Seattle WA, US

International Classification:

A61K 39/00
C12N 5/0783
C07K 16/30
C07K 14/705
C07K 14/725
A61K 45/06
A61P 35/00

Abstract:

Genetically modified compositions, such as adenoviral vectors and T cells, for treating diseases such as cancer and infectious diseases are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating diseases such as cancer and infectious diseases.

US Patent:

20190022209, Jan 24, 2019

Filed:

Jan 13, 2017

Appl. No.:

16/070104

Inventors:

- Seattle WA, US
Joseph Balint - Seattle WA, US
Elizabeth Gabitzsch - Seattle WA, US
Yvette Latchman - Seattle WA, US
Adrian Rice - Seattle WA, US

International Classification:

A61K 39/145

Abstract:

Methods for constructing and producing a recombinant adenovirus based vector vaccine containing multiple influenza antigen genes for use in generating broad based immune responses against influenza A and B viruses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus are described. Specifically, the recombinant adenovirus based vector is a replication defective adenovirus vector comprising a deletion in an early 2b (E2b) gene.

US Patent:

20180344832, Dec 6, 2018

Filed:

Apr 20, 2016

Appl. No.:

15/564413

Inventors:

- Seattle WA, US
Elizabeth GABITZSCH - Seattle WA, US
Yvette LATCHMAN - Seattle WA, US
Adrian RICE - Seattle WA, US

International Classification:

A61K 39/00
A61K 39/395
A61K 31/519
A61K 31/513
A61K 31/282
A61K 38/17
C12N 15/86

Abstract:

Methods and compositions for generating immune responses using adenovirus vectors that allow multiple vaccinations or in combination with other therapy and vaccinations in individuals with preexisting immunity to adenovirus are provided.

Address:

2247 S 308 St, Federal Way, WA 98003

Phone:

(253)9413382

VIN:

4S4BP62C356384502

Make:

SUBARU

Model:

OUTBACK

Year:

2007