Aguan D Wei

US Patent:

20020055537, May 9, 2002

Filed:

Nov 16, 2001

Appl. No.:

09/987809

Inventors:

Uwe Gerlach - Hattersheim, DE
Joachim Hofmann - Bad Camberg, DE
Hans Lang - Hofheim, DE
Aguan Wei - Saint Louis MO, US

Assignee:

Aventis Pharma Deutschland GMBH

International Classification:

A61K031/352
A01N043/16

US Classification:

514/456000

Abstract:

Use of inhibitors of the KQT1 channel for preparing a medicament for treating diseases caused by helminths and ectoparasites Inhibitors of the KQT1 channel are a novel way of destroying helminths and ectoparasites. For this reason, blockers of the cellular KQT1 channel, which is present in helminths and ectoparasites, are used for preparing a medicament for the treatment of vertebrates and humans infested by helminths or ectoparasites. These KQT1 blockers are used as medicaments on their own or in combination with other medicaments and therapeutic measures. Inhibitors of the KQT1 channel are likewise a novel mechanism of action for phytoparasites such as insects, arachnids, molluscs and nematodes, and consequently, they are used for preparing a crop protection composition.

US Patent:

6335363, Jan 1, 2002

Filed:

Dec 16, 1999

Appl. No.:

09/461806

Inventors:

Uwe Gerlach - Hattersheim, DE
Joachim Hofmann - Bad Camberg, DE
Hans Jochen Lang - Hofheim, DE
Aguan Wei - Saint Louis MO

Assignee:

Aventis Pharma Deutschland GmbH - Frankfurt am Main

International Classification:

A61K 3135

US Classification:

514456, 514457

Abstract:

Use of inhibitors of the KQT1 channel for preparing a medicament for treating diseases caused by helminths and ectoparasites Inhibitors of the KQT1 channel are a novel way of destroying helminths and ectoparasites. For this reason, blockers of the cellular KQT1 channel, which is present in helminths and ectoparasites, are used for preparing a medicament for the treatment of vertebrates and humans infested by helminths or ectoparasites. These KQT1 blockers are used as medicaments on their own or in combination with other medicaments and therapeutic measures. Inhibitors of the KQT1 channel are likewise a novel mechanism of action for phytoparasites such as insects, arachnids, molluscs and nematodes, and consequently, they are used for preparing a crop protection composition.