Andrew L. Feldman - Rochester MN, US Ahmet Dogan - Rochester MN, US George Vasmatzis - Oronoco MN, US Mark Law - Rochester MN, US David I. Smith - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 31/713 C12Q 1/68 G01N 33/68 A61P 35/00
US Classification:
514 44 A, 435 6, 435 71
Abstract:
This document relates to the activity of interferon regulatory factor 4 (IRF4) in T-cell lymphomas. For example, methods and materials involved in reducing the expression of an IRF4 polypeptide in T-cell lymphoma cells and identifying agents having the ability to reduce expression of an IRF4 polypeptide in T-cell lymphoma cells are provided. This document also relates to reducing DUSP22 or FLJ43663 polypeptide activity in T-cell lymphomas. For example, methods and materials involved in reducing the expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells and identifying agents having the ability to reduce expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells are provided.
Reducing Irf4, Dusp22, Or Flj43663 Polypeptide Expression
Andrew L. Feldman - Rochester MN, US Ahmet Dogan - Rochester MN, US George Vasmatzis - Oronoco MN, US Mark Law - Rochester MN, US David I. Smith - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
C40B 30/04 C12Q 1/42 G01N 33/573 C12Q 1/68
US Classification:
506 9, 435 618, 435 21, 435 71
Abstract:
This document relates to the activity of interferon regulatory factor 4 (IRF4) in T-cell lymphomas. For example, methods and materials involved in reducing the expression of an IRF4 polypeptide in T-cell lymphoma cells and identifying agents having the ability to reduce expression of an IRF4 polypeptide in T-cell lymphoma cells are provided. This document also relates to reducing DUSP22 or FLJ43663 polypeptide activity in T-cell lymphomas. For example, methods and materials involved in reducing the expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells and identifying agents having the ability to reduce expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells are provided.
Steven R. Zeldenrust - Rochester MN, US David R. Barnidge - Rochester MN, US Ahmet Dogan - Rochester MN, US Julie A. Vrana - Rochester MN, US Jeffrey D. Gamez - Rochester MN, US Jason D. Theis - Kasson MN, US
International Classification:
C12Q 1/37
US Classification:
435 23
Abstract:
This document provides methods and materials related to determining the identity of amyloid polypeptides in biological samples. For examples, methods and materials for identifying an amyloid polypeptide present in a fat aspirate are provided herein.